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Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)
NCT04202341 · View on ClinicalTrials.gov ↗
Study Summary
Long-term, multicenter, multinational, observational, registry of patients with gMG that is designed to collect data on clinical outcomes and safety in patients prescribed Alexion C5 inhibitor therapies (C5IT) such as eculizumab (Soliris®) and ravulizumab (Ultomiris®).
Conditions Studied
Study Locations (20)
California
- Clinical Trial Site — Fresno
- Clinical Trial Site — Orange
- Clinical Trial Site — Rancho Mirage
- Clinical Trial Site — Sylmar
Florida
- Clinical Trial Site — Clearwater
- Clincal Trial Site — Gainesville
- Clinical Trial Site — Jacksonville
- Clinical Trial Site — Tampa
Colorado
- Clinical Trial Site — Colorado Springs
- Clinical Trial Site — Fort Collins
Alabama
- Clinical Trial Site — Birmingham
Arizona
- Clinical Trial Site — Scottsdale
Connecticut
- Clinical Trial Site — New Haven
District of Columbia
- Clinical Trial Site — Washington D.C.
Georgia
- Clinical Trial Site — Augusta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 500 participants |
| Start Date | 2019-12-02 |
| Est. Completion | 2029-10-01 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04202341
The ClinicalTrials.gov registry entry for NCT04202341 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 500 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Alexion Pharmaceuticals, which has 109 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Generalized Myasthenia Gravis appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04202341 reports 20 study locations spanning 13 distinct geographic areas — top geographies include California, Florida, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04202341 about?
NCT04202341 is a clinical study titled "Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)". Long-term, multicenter, multinational, observational, registry of patients with gMG that is designed to collect data on clinical outcomes and safety in patients prescribed Alexion C5 inhibitor therapies (C5IT) such as eculizumab (Soliris®) and ravulizumab (Ultomiris®).
What is the current status of trial NCT04202341?
This trial is currently recruiting. The enrollment target is 500 participants. The study started on 2019-12-02. Estimated completion is 2029-10-01.
What conditions does trial NCT04202341 study?
This clinical trial studies the following conditions: Generalized Myasthenia Gravis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT04202341?
This trial is sponsored by Alexion Pharmaceuticals, which has 109 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04202341 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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