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NCT06034509 · ClinicalTrials.gov registry record

Cognitive and Vascular Functioning Following TBI

A clinical trial of Traumatic Brain Injury and Cognitive Decline, sponsored by Walter Reed National Military Medical Center.

Recruiting
Registry status
300
Enrollment target
1
Study location

NCT06034509: Recruiting study of Traumatic Brain Injury and Cognitive Decline, sponsored by Walter Reed National Military Medical Center.

NCT06034509 is a study of Traumatic Brain Injury and Cognitive Decline that is actively recruiting participants, run by Walter Reed National Military Medical Center. The registered enrollment target is 300 participants, roughly in line with the 276-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06034509, a study of Traumatic Brain Injury and Cognitive Decline, is actively recruiting participants, sponsored by Walter Reed National Military Medical Center.

RECRUITING
Registry status
300 participants
Enrollment target
1
Study location

Study Summary

This observational study will examine the association of chronic traumatic cerebrovascular injury and cardiovascular risk factors with TBI-related cognitive impairment and vascular dementia. Cerebrovascular, inflammatory, and neurodegenerative blood biomarkers as well as clinical and neuroimaging data

Primary Outcome

A panel of blood biomarkers including vascular (e.g., vascular endothelial growth factor, von Willebrand Factor, cholesterol, lipoproteins, homocysteine, fibrinogen, hemoglobin A1C), inflammatory (e.g., high sensitivity c-reactive protein, Tumor Necrosis Factor-alpha, IL-6, IL-12p70, YKL-40), and neuronal degeneration (e.g., neurofilament light, Glial Fibrillary Acidic Protein, phosphorylated tau, Clusterin, brain-derived neurotrophic factor, beta amyloid proteins) will be compared between TBI g

Conditions Studied

Traumatic Brain Injury Cognitive Decline Vascular Dementia

Interventions

  • OTHER No intervention. This is an observational study.

Study Locations (1)

Maryland

  • Walter Reed National Military Medical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2023-11-27
Est. Completion 2027-05
Walter Reed National Military Medical Center

48 total trials

What NCT06034509 shows while recruiting

NCT06034509 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 276-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target.

The record links to 3 conditions, with Traumatic Brain Injury appearing as the primary indexed condition, and to 1 intervention - of which No intervention. This is an observational study. is the first listed.

NCT06034509 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT06034509 about?

NCT06034509 is a clinical study titled "Cognitive and Vascular Functioning Following TBI". This observational study will examine the association of chronic traumatic cerebrovascular injury and cardiovascular risk factors with TBI-related cognitive impairment and vascular dementia. Cerebrovascular, inflammatory, and neurodegenerative blood biomarkers as well as clinical and neuroimaging da...

What is the current status of trial NCT06034509?

This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2023-11-27. Estimated completion is 2027-05.

What conditions does trial NCT06034509 study?

This clinical trial studies the following conditions: Traumatic Brain Injury, Cognitive Decline, Vascular Dementia.

What interventions are being tested in trial NCT06034509?

The interventions under investigation include: No intervention. This is an observational study. (OTHER).

Who is sponsoring clinical trial NCT06034509?

This trial is sponsored by Walter Reed National Military Medical Center, which has 48 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06034509 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Traumatic Brain Injury

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06034509's enrollment target sits among peer trials

300 20th of 171 higher than 146 of 171 other Traumatic Brain Injury trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Traumatic Brain Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT06034509

Source: ClinicalTrials.gov NCT06034509, the US trial registry maintained by the National Library of Medicine. NCT06034509 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.