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NCT05998863 · ClinicalTrials.gov registry record · Phase 3
EffCaMgCit to Prevent Mineral Metabolism and Renal Complications of Chronic PPI Therapy
A Phase 3 study of Osteoporosis and Hypomagnesemia, sponsored by University of Texas Southwestern Medical Center.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 56
- Enrollment target
- 2
- Study locations
NCT05998863: Recruiting Phase 3 study of Osteoporosis and Hypomagnesemia, sponsored by University of Texas Southwestern Medical Center.
NCT05998863 is a Phase 3 study of Osteoporosis and Hypomagnesemia that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 56 participants, below the 1,545-participant average among 84 other Osteoporosis trials with a reported enrollment target (96% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05998863, a Phase 3 study of Osteoporosis and Hypomagnesemia, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 56 participants
- Enrollment target
- 2
- Study locations
Study Summary
Proton pump inhibitors (PPIs) are widely used for the control of gastric ulcer-gastritis, erosive esophagitis (gastroesophageal reflux disease), peptic ulcer disease (duodenal ulcer), and heartburn. Despite their efficacy, their use has been implicated in possibly causing fragility fractures (osteoporosis), hypomagnesemia (magnesium deficiency) and increased risk of chronic kidney disease (CKD). The current trial represents the investigators ongoing effort to discern whether these complications could be averted by effervescent calcium magnesium citrate (EffCaMgCit).
Conditions Studied
Interventions
- OTHER Placebo
- DRUG EffCaMgCit
Study Locations (2)
Texas
- University of Texas Southwestern Medical Center - Dallas
- UT Southwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2024-04-19 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 3 |
What NCT05998863 shows while recruiting
NCT05998863 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 1,545-participant average among 84 other Osteoporosis trials with a reported enrollment target (96% lower).
The record links to 2 conditions, with Osteoporosis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05998863 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05998863 about?
NCT05998863 is a clinical study titled "EffCaMgCit to Prevent Mineral Metabolism and Renal Complications of Chronic PPI Therapy". Proton pump inhibitors (PPIs) are widely used for the control of gastric ulcer-gastritis, erosive esophagitis (gastroesophageal reflux disease), peptic ulcer disease (duodenal ulcer), and heartburn. Despite their efficacy, their use has been implicated in possibly causing fragility fractures (osteop...
What is the current status of trial NCT05998863?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 56 participants. The study started on 2024-04-19. Estimated completion is 2026-12-31.
What conditions does trial NCT05998863 study?
This clinical trial studies the following conditions: Osteoporosis, Hypomagnesemia.
What interventions are being tested in trial NCT05998863?
The interventions under investigation include: Placebo (OTHER), EffCaMgCit (DRUG).
Who is sponsoring clinical trial NCT05998863?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05998863 being conducted?
This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoporosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05998863's enrollment target sits among peer trials
56 52nd of 84 higher than 33 of 84 other Osteoporosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoporosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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