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NCT00049829 · ClinicalTrials.gov registry record · Phase 3
HORIZON-PFT: Pivotal Fracture Trial
A Phase 3 study of Osteoporosis, sponsored by Novartis Pharmaceuticals.
- Completed
- Registry status
- Phase 3
- Development phase
- 7,700
- Enrollment target
- 20
- Study locations
NCT00049829: Completed Phase 3 study of Osteoporosis, sponsored by Novartis Pharmaceuticals.
NCT00049829 is a Phase 3 study of Osteoporosis that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 7,700 participants, above the 1,454-participant average among 84 other Osteoporosis trials with a reported enrollment target (430% higher). The trial reports 20 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00049829, a Phase 3 study of Osteoporosis, has completed, sponsored by Novartis Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 7,700 participants
- Enrollment target
- 20
- Study locations
Study Summary
HORIZON-PFT (Pivotal Fracture Trial) will study the effect of zoledronic acid, given once per year, on the treatment of osteoporosis in women past menopause. Hip and vertebral fractures are the most devastating consequences of osteoporosis. HORIZON-PFT is designed to determine the benefits of zoledronic acid in fracture reduction at both the hip and spine.
Conditions Studied
Interventions
- DRUG Zoledronic Acid
Study Locations (20)
California
- Osteoporosis Medical Center - Beverly Hills
- Orthopaedic Hospital - Los Angeles
- The Foundation for Osteoporosis Research and Education - Oakland
- University of California Davis- Gen Med Research - Sacramento
- Osteoporosis Prevention Center - San Diego
- Radiant Research- San Diego - San Diego
- Diablo Clinical Research, Inc - Walnut Creek
Florida
- CRA Research - Fort Lauderdale
- Anchor Research Center - Naples
- Sarasota Arthritis Center - Sarasota
- Radiant - Stuart
- Comprehensive Clinical Trials, LLC - West Palm Beach
Arizona
- Arizona Arthritis Research - Paradise Valley
- Southern Arizona VA - Tucson
Colorado
- Colorado Center for Bone Research - Lakewood
- Longmont Medical Research Network - Longmont
Alabama
- University of Alabama at Birmingham - Birmingham
Arkansas
- University of Arkansas for Medical Science - Little Rock
Connecticut
- Northeast Clinical Research - Hamden
Delaware
- Health Core - Newark
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7,700 participants |
| Start Date | 2002-01 |
| Phase | Phase 3 |
What the finished NCT00049829 record still lists
NCT00049829 is an interventional study that assigns participants to a tested intervention. Its 7,700 participants enrollment target places it among the larger protocols in the corpus, above the 1,454-participant average among 84 other Osteoporosis trials with a reported enrollment target (430% higher).
The record links to 1 condition, with Osteoporosis appearing as the primary indexed condition, and to 1 intervention - of which Zoledronic Acid is the first listed.
NCT00049829 names 20 study sites across 8 states, led by California, Florida, Arizona.
Frequently Asked Questions
What is clinical trial NCT00049829 about?
NCT00049829 is a clinical study titled "HORIZON-PFT: Pivotal Fracture Trial". HORIZON-PFT (Pivotal Fracture Trial) will study the effect of zoledronic acid, given once per year, on the treatment of osteoporosis in women past menopause. Hip and vertebral fractures are the most devastating consequences of osteoporosis. HORIZON-PFT is designed to determine the benefits of zoledr...
What is the current status of trial NCT00049829?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 7,700 participants. The study started on 2002-01.
What conditions does trial NCT00049829 study?
This clinical trial studies the following conditions: Osteoporosis.
What interventions are being tested in trial NCT00049829?
The interventions under investigation include: Zoledronic Acid (DRUG).
Who is sponsoring clinical trial NCT00049829?
This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00049829 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoporosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00049829's enrollment target sits among peer trials
7,700 3rd of 84 higher than 82 of 84 other Osteoporosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoporosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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