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RECRUITING Phase 2

Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors (NETs) of the Gastrointestinal Tract, Lung, or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors

NCT05997056 · View on ClinicalTrials.gov ↗

Study Summary

A Phase 2 multi-center, open-label, single arm study of nab-sirolimus in patients with well-differentiated neuroendocrine tumors (NETs) of the gastrointestinal tract, lung, or pancreas who have not received prior treatment with mTOR inhibitors

Interventions

  • DRUG nab-sirolimus

Study Locations (4)

California

  • Hoag Memorial Hospital Presbyterian — Newport Beach

Colorado

  • Rocky Mountain Cancer Centers — Denver

Texas

  • Texas Oncology — Dallas

Wisconsin

  • Medical College of Wisconsin Cancer Center — Milwaukee

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2023-11-07
Est. Completion 2025-12-08
Phase Phase 2

Sponsor

Aadi Bioscience

5 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05997056

The ClinicalTrials.gov registry entry for NCT05997056 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Aadi Bioscience, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 5 conditions, with Neuroendocrine Tumors appearing as the primary indexed condition, and to 1 intervention — of which nab-sirolimus is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05997056 reports 4 study locations spanning 4 distinct geographic areas — top geographies include California, Colorado, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05997056 about?

NCT05997056 is a clinical study titled "Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors (NETs) of the Gastrointestinal Tract, Lung, or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors". A Phase 2 multi-center, open-label, single arm study of nab-sirolimus in patients with well-differentiated neuroendocrine tumors (NETs) of the gastrointestinal tract, lung, or pancreas who have not received prior treatment with mTOR inhibitors

What is the current status of trial NCT05997056?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 21 participants. The study started on 2023-11-07. Estimated completion is 2025-12-08.

What conditions does trial NCT05997056 study?

This clinical trial studies the following conditions: Neuroendocrine Tumors, Pancreatic Neuroendocrine Tumor, NET, Gastrointestinal Neuroendocrine Tumor, Pulmonary Neuroendocrine Tumor. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05997056?

The interventions under investigation include: nab-sirolimus (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05997056?

This trial is sponsored by Aadi Bioscience, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05997056 being conducted?

This trial has 4 study locations across California, Colorado, Texas, Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial