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NCT05838560 · ClinicalTrials.gov registry record · Phase 2

Dasatinib Plus Quercetin for Accelerated Aging in Mental Disorders

A Phase 2 study of Schizophrenia and Treatment-Resistant Depression, sponsored by Washington University School of Medicine.

Active
Registry status
Phase 2
Development phase
40
Enrollment target
1
Study location

NCT05838560 is a Phase 2 study of Schizophrenia and Treatment-Resistant Depression that is active but no longer recruiting, run by Washington University School of Medicine. The registered enrollment target is 40 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05838560, a Phase 2 study of Schizophrenia and Treatment-Resistant Depression, is active but no longer recruiting, sponsored by Washington University School of Medicine.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

This pilot open-label study examines the effects of a combination of dasatinib plus quercetin - two drugs that have known senolytics properties - on physiological aging in older individuals with depression or schizophrenia.

Interventions

  • DRUG Dasatinib
  • DRUG quercetin

Study Locations (1)

Missouri

  • Washington University School of Medicine - St Louis

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2023-07-01
Est. Completion 2026-08-01
Phase Phase 2

What the Registry Record Tells You About NCT05838560

The ClinicalTrials.gov registry entry for NCT05838560 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (82% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Schizophrenia appearing as the primary indexed condition, and to 2 interventions - of which Dasatinib is the first listed.

NCT05838560 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.

Frequently Asked Questions

What is clinical trial NCT05838560 about?

NCT05838560 is a clinical study titled "Dasatinib Plus Quercetin for Accelerated Aging in Mental Disorders". This pilot open-label study examines the effects of a combination of dasatinib plus quercetin - two drugs that have known senolytics properties - on physiological aging in older individuals with depression or schizophrenia.

What is the current status of trial NCT05838560?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2023-07-01. Estimated completion is 2026-08-01.

What conditions does trial NCT05838560 study?

This clinical trial studies the following conditions: Schizophrenia, Treatment-Resistant Depression, Aging, Premature.

What interventions are being tested in trial NCT05838560?

The interventions under investigation include: Dasatinib (DRUG), quercetin (DRUG).

Who is sponsoring clinical trial NCT05838560?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05838560 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.