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NCT05838547 · ClinicalTrials.gov registry record
CANF-Comb-II PET-MR in Atherosclerosis Multisite
A clinical trial of Carotid Atherosclerosis and Asymptomatic Carotid Artery Stenosis, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- 80
- Enrollment target
- 2
- Study locations
NCT05838547 is a study of Carotid Atherosclerosis and Asymptomatic Carotid Artery Stenosis that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 80 participants, below the 157-participant average among 5 other Carotid Atherosclerosis trials with a reported enrollment target (49% lower). The trial reports 2 study locations across 2 states.
The verdict
NCT05838547, a study of Carotid Atherosclerosis and Asymptomatic Carotid Artery Stenosis, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- 80 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this observational study is to learn more about plaque biology in asymptomatic carotid artery stenosis (ACAS) patients through imaging. The main questions it aims to answer are: * To determine the ability of 64Cu-CANF-Comb positron emission tomography (PET) to risk stratify ACAS patients for stroke event, to include transient ischemic attack or remote ipsilateral intervention. * To further understand the role of Natriuretic Peptide Receptor C (NPRC) in the evolution of carotid atherosclerosis. Participants will be asked to undergo a carotid PET-magnetic resonance imaging (MRI) examination to assess whether the carotid atherosclerosis uptake of 64Cu-CANF-Comb as measured by PET-MRI correlates with patient outcomes (stroke, transient ischemic attack, or remote ipsilateral intervention).
Conditions Studied
Interventions
- DRUG 64Cu-25%-CANF-Comb
Study Locations (2)
California
- Cedars Sinai Medical Center - Los Angeles
Missouri
- Washington University in St. Louis - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2023-03-21 |
| Est. Completion | 2027-05-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05838547
The ClinicalTrials.gov registry entry for NCT05838547 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 157-participant average among 5 other Carotid Atherosclerosis trials with a reported enrollment target (49% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Carotid Atherosclerosis appearing as the primary indexed condition, and to 1 intervention - of which 64Cu-25%-CANF-Comb is the first listed.
NCT05838547 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Missouri.
Frequently Asked Questions
What is clinical trial NCT05838547 about?
NCT05838547 is a clinical study titled "CANF-Comb-II PET-MR in Atherosclerosis Multisite". The goal of this observational study is to learn more about plaque biology in asymptomatic carotid artery stenosis (ACAS) patients through imaging. The main questions it aims to answer are: * To determine the ability of 64Cu-CANF-Comb positron emission tomography (PET) to risk stratify ACAS patient...
What is the current status of trial NCT05838547?
This trial is currently recruiting. The enrollment target is 80 participants. The study started on 2023-03-21. Estimated completion is 2027-05-31.
What conditions does trial NCT05838547 study?
This clinical trial studies the following conditions: Carotid Atherosclerosis, Asymptomatic Carotid Artery Stenosis, Carotid Artery Atheroma.
What interventions are being tested in trial NCT05838547?
The interventions under investigation include: 64Cu-25%-CANF-Comb (DRUG).
Who is sponsoring clinical trial NCT05838547?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05838547 being conducted?
This trial has 2 study locations across California, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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