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NCT05822388 · ClinicalTrials.gov registry record
Cognitive Decline Following Deep Brain Stimulation
A clinical trial of Parkinson Disease and Movement Disorders, sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- 80
- Enrollment target
- 1
- Study location
NCT05822388: Recruiting study of Parkinson Disease and Movement Disorders, sponsored by Medical University of South Carolina.
NCT05822388 is a study of Parkinson Disease and Movement Disorders that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 80 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05822388, a study of Parkinson Disease and Movement Disorders, is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
This research study aims to identify MRI-based brain biomarkers that predict an individual's response to Deep Brain Stimulation (DBS). In particular, this study will focus on changes in cognition associated with DBS. A total of 55 participants with Parkinson's Disease planning to undergo DBS will be recruited from MUSCs Clinical DBS Program. Participants will undergo four visits, including a 1-hour screening visit, a 1.5-hour pre-DBS MRI scanning visit, and a 3.5-hour post-DBS cognitive assessment visit. In addition control participants without Parkinson's Disease will be recruited to undergo MRI scanning and cognitive assessments.
Primary Outcome
Change in cognitive performance using a comprehensive neuropsychological battery (e.g., language, executive control, memory, and attention)
Conditions Studied
Interventions
- PROCEDURE Deep Brain Stimulation Surgical Procedures as Part of Routine Clinical Care
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2023-04-01 |
| Est. Completion | 2026-03-31 |
What NCT05822388 shows while recruiting
NCT05822388 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Parkinson Disease appearing as the primary indexed condition, and to 1 intervention - of which Deep Brain Stimulation Surgical Procedures as Part of Routine Clinical Care is the first listed.
NCT05822388 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT05822388 about?
NCT05822388 is a clinical study titled "Cognitive Decline Following Deep Brain Stimulation". This research study aims to identify MRI-based brain biomarkers that predict an individual's response to Deep Brain Stimulation (DBS). In particular, this study will focus on changes in cognition associated with DBS. A total of 55 participants with Parkinson's Disease planning to undergo DBS will be...
What is the current status of trial NCT05822388?
This trial is currently recruiting. The enrollment target is 80 participants. The study started on 2023-04-01. Estimated completion is 2026-03-31.
What conditions does trial NCT05822388 study?
This clinical trial studies the following conditions: Parkinson Disease, Movement Disorders.
What interventions are being tested in trial NCT05822388?
The interventions under investigation include: Deep Brain Stimulation Surgical Procedures as Part of Routine Clinical Care (PROCEDURE).
Who is sponsoring clinical trial NCT05822388?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05822388 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05822388's enrollment target sits among peer trials
80 105th of 297 higher than 189 of 297 other Parkinson Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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