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ACTIVE NOT RECRUITING

Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study

NCT05797896 · View on ClinicalTrials.gov ↗

Study Summary

An observational study to investigate the natural history and evaluate biomarkers of participants with geographic atrophy secondary to age-related macular degeneration

Study Locations (20)

Other

  • Belfast City Hospital — Belfast
  • Bradford Royal Infirmary — Bradford
  • Frimley Park Hospital — Frimley
  • Gloucestershire Royal Hospital — Gloucester
  • Liverpool Hospital — Liverpool
  • Moorfields Eye Hospital — London
  • Western Eye Hospital — London
  • Manchester Royal Eye Hospital — Manchester
  • Newcastle Hospital — Newcastle
  • Nottingham City Hospital — Nottingham

Texas

  • Retina Research Institute of Texas — Abilene
  • Texas Retina Associates — Plano
  • San Antonio Eye Center — San Antonio

California

  • Global Research Management — Glendale
  • Northern California Retina Vitreous Associates — Mountain View

Indiana

  • Midwest Eye Institute — Carmel

Maryland

  • Mid Atlantic Retina Specialists — Hagerstown

Nevada

  • Sierra Eye Associates — Reno

Oregon

  • Verum Research LLC — Eugene

Pennsylvania

  • Mid Atlantic Retina — Philadelphia

Trial Details

FieldValue
Enrollment Target 250 participants
Start Date 2023-02-07
Est. Completion 2027-07-31

Sponsor

Complement Therapeutics

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05797896

The ClinicalTrials.gov registry entry for NCT05797896 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 250 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Complement Therapeutics, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 7 conditions, with Eye Diseases appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05797896 reports 20 study locations spanning 8 distinct geographic areas — top geographies include Other, Texas, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05797896 about?

NCT05797896 is a clinical study titled "Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study". An observational study to investigate the natural history and evaluate biomarkers of participants with geographic atrophy secondary to age-related macular degeneration

What is the current status of trial NCT05797896?

This trial is currently active not recruiting. The enrollment target is 250 participants. The study started on 2023-02-07. Estimated completion is 2027-07-31.

What conditions does trial NCT05797896 study?

This clinical trial studies the following conditions: Eye Diseases, Geographic Atrophy, Macular Degeneration, Retinal Disease, Retinal Degeneration. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

Who is sponsoring clinical trial NCT05797896?

This trial is sponsored by Complement Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05797896 being conducted?

This trial has 20 study locations across California, Indiana, Maryland, Nevada, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial