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NCT05778734 · ClinicalTrials.gov registry record · NA
StuDy AimED at Increasing AlCohol AbsTinEnce
A NA study of Alcohol Use Disorder, sponsored by University of Illinois at Chicago.
- Recruiting
- Registry status
- NA
- Development phase
- 104
- Enrollment target
- 1
- Study location
NCT05778734 is a NA study of Alcohol Use Disorder that is actively recruiting participants, run by University of Illinois at Chicago. The registered enrollment target is 104 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (68% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05778734, a NA study of Alcohol Use Disorder, is actively recruiting participants, sponsored by University of Illinois at Chicago.
- RECRUITING
- Registry status
- NA
- Development phase
- 104 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to test the feasibility \& acceptability of an integrated CM-PST intervention (in K99 phase) and preliminary efficacy (in R00 phase), vs. CM alone, to improve treatment efficacy and inform about neural mechanisms of treatment effects in young adults with Alcohol Use Disorder (AUD). The aims are as follows: K99 Aim: Test feasibility \& acceptability of a developed CM-PST, by meeting these benchmarks: 2a Feasibility: enroll 20 participants in the new CM-PST in a single-arm pre- and post-study, and retain ≥85% at wk 12. 2b Deliver CM-PST at ≥90% fidelity to intervention protocol. 2c Acceptability to participants: Achieve mean score ≥3 on Client Satisfaction Scale Questionnaire and satisfaction from semi-structured interviews. R00 Aim 1) Test preliminary efficacy of CM-PST in a 2-arm pilot RCT: Male/female young adults (aged18-24) who meet AUD criteria will be randomized to CM-PST or CM-only control, and assessed at baseline (0), 3, and 6 months. Primary study endpoint will be 3 months. R00 Aim 2 (Exploratory) Explore potential neural mechanisms of CM-PST effects, by fMRI scanning \& analyses of core regions of the brain circuits regulating positive affect (ventral striatum), negative affect (amygdala), and cognitive control (dorsolateral prefrontal cortex), and connectivity between these core regions.
Conditions Studied
Interventions
- BEHAVIORAL CM-PST
- BEHAVIORAL CM only
Study Locations (1)
Illinois
- University of Illinois at Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 104 participants |
| Start Date | 2023-07-30 |
| Est. Completion | 2028-05-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05778734
The ClinicalTrials.gov registry entry for NCT05778734 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 104 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (68% lower). The listed sponsor is University of Illinois at Chicago, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Alcohol Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which CM-PST is the first listed.
NCT05778734 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT05778734 about?
NCT05778734 is a clinical study titled "StuDy AimED at Increasing AlCohol AbsTinEnce". The goal of this clinical trial is to test the feasibility \& acceptability of an integrated CM-PST intervention (in K99 phase) and preliminary efficacy (in R00 phase), vs. CM alone, to improve treatment efficacy and inform about neural mechanisms of treatment effects in young adults with Alcohol Us...
What is the current status of trial NCT05778734?
This trial is currently recruiting. It is a NA study. The enrollment target is 104 participants. The study started on 2023-07-30. Estimated completion is 2028-05-31.
What conditions does trial NCT05778734 study?
This clinical trial studies the following conditions: Alcohol Use Disorder.
What interventions are being tested in trial NCT05778734?
The interventions under investigation include: CM-PST (BEHAVIORAL), CM only (BEHAVIORAL).
Who is sponsoring clinical trial NCT05778734?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05778734 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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