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NCT05767736 · ClinicalTrials.gov registry record

A Study to Evaluate Long-Term Safety of Vumerity and Tecfidera in Participants With Multiple Sclerosis (MS)

A clinical trial of Multiple Sclerosis, sponsored by Biogen.

Active
Registry status
10,500
Enrollment target
1
Study location

NCT05767736 is a study of Multiple Sclerosis that is active but no longer recruiting, run by Biogen. The registered enrollment target is 10,500 participants, above the 552-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (1802% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT05767736, a study of Multiple Sclerosis, is active but no longer recruiting, sponsored by Biogen.

ACTIVE NOT RECRUITING
Registry status
10,500 participants
Enrollment target
1
Study location

Study Summary

The primary objective of the study is to estimate the incidence rate of serious adverse events (SAEs), including but not limited to malignancies and serious and opportunistic infections, among participants with MS treated with Vumerity, Tecfidera, other selected disease modifying therapies (DMTs \[teriflunomide, beta interferons, or glatiramer acetate\]), or Vumerity after switching from Tecfidera. The secondary objective of the study is to compare the incidence rate of SAEs, including but not limited to malignancies and serious and opportunistic infections, among MS participants treated with Vumerity, Tecfidera, and Vumerity after switching from Tecfidera with the incidence rate of MS participants treated with other selected DMTs (teriflunomide, beta-interferons, or glatiramer acetate), if the sample size allows.

Conditions Studied

Interventions

  • DRUG Diroximel Fumarate
  • DRUG Dimethyl Fumarate
  • DRUG Disease-Modifying Therapies (DMTs)

Study Locations (1)

Massachusetts

  • Research Site - Cambridge

Trial Details

FieldValue
Enrollment Target 10,500 participants
Start Date 2024-06-08
Est. Completion 2032-12-01

Sponsor

Biogen

334 total trials

What the Registry Record Tells You About NCT05767736

The ClinicalTrials.gov registry entry for NCT05767736 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 10,500 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 552-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (1802% higher). The listed sponsor is Biogen, which has 334 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 3 interventions - of which Diroximel Fumarate is the first listed.

NCT05767736 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05767736 about?

NCT05767736 is a clinical study titled "A Study to Evaluate Long-Term Safety of Vumerity and Tecfidera in Participants With Multiple Sclerosis (MS)". The primary objective of the study is to estimate the incidence rate of serious adverse events (SAEs), including but not limited to malignancies and serious and opportunistic infections, among participants with MS treated with Vumerity, Tecfidera, other selected disease modifying therapies (DMTs \[t...

What is the current status of trial NCT05767736?

This trial is currently active not recruiting. The enrollment target is 10,500 participants. The study started on 2024-06-08. Estimated completion is 2032-12-01.

What conditions does trial NCT05767736 study?

This clinical trial studies the following conditions: Multiple Sclerosis.

What interventions are being tested in trial NCT05767736?

The interventions under investigation include: Diroximel Fumarate (DRUG), Dimethyl Fumarate (DRUG), Disease-Modifying Therapies (DMTs) (DRUG).

Who is sponsoring clinical trial NCT05767736?

This trial is sponsored by Biogen, which has 334 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05767736 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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