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NCT05745883 · ClinicalTrials.gov registry record · Phase 1
Study of DISC-0974 to Assess the Safety, Tolerability, PK and PD of DISC-0974 in Participants With CKD and Anemia
A Phase 1 study of Chronic Kidney Diseases and Anemia of Chronic Kidney Disease, sponsored by Disc Medicine.
- Active
- Registry status
- Phase 1
- Development phase
- 50
- Enrollment target
- 13
- Study locations
NCT05745883: Active Phase 1 study of Chronic Kidney Diseases and Anemia of Chronic Kidney Disease, sponsored by Disc Medicine.
NCT05745883 is a Phase 1 study of Chronic Kidney Diseases and Anemia of Chronic Kidney Disease that is active but no longer recruiting, run by Disc Medicine. The registered enrollment target is 50 participants, below the 444-participant average among 73 other Chronic Kidney Diseases trials with a reported enrollment target (89% lower). The trial reports 13 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05745883, a Phase 1 study of Chronic Kidney Diseases and Anemia of Chronic Kidney Disease, is active but no longer recruiting, sponsored by Disc Medicine.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 50 participants
- Enrollment target
- 13
- Study locations
Study Summary
This Phase 1b study of DISC-0974 will assess the safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney Disease and Anemia.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG DISC-0974
Study Locations (13)
Florida
- Accel Research - DeLand
- Total Research Group - Miami
- Flourish Research - Winter Park
Texas
- Clinical Advancement Center, PLLC - San Antonio
- Endeavor Clinical Trials - San Antonio
California
- UCLA Clinical and Translational Research - Los Angeles
Colorado
- US Renal Care Inc. - Lone Tree
Georgia
- Nephrology and Hypertension Specialists, PC-Dalton - Dalton
Idaho
- CARE Institute - Boise Kidney - Boise
Michigan
- Center for Advanced Kidney Research PLC - Saint Clair Shores
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2023-04-04 |
| Est. Completion | 2026-05 |
| Phase | Phase 1 |
What the registry record for NCT05745883 still lists
NCT05745883 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 444-participant average among 73 other Chronic Kidney Diseases trials with a reported enrollment target (89% lower).
The record links to 2 conditions, with Chronic Kidney Diseases appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05745883 lists 13 locations in 10 states (Florida, Texas, California).
Frequently Asked Questions
What is clinical trial NCT05745883 about?
NCT05745883 is a clinical study titled "Study of DISC-0974 to Assess the Safety, Tolerability, PK and PD of DISC-0974 in Participants With CKD and Anemia". This Phase 1b study of DISC-0974 will assess the safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney Disease and Anemia.
What is the current status of trial NCT05745883?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2023-04-04. Estimated completion is 2026-05.
What conditions does trial NCT05745883 study?
This clinical trial studies the following conditions: Chronic Kidney Diseases, Anemia of Chronic Kidney Disease.
What interventions are being tested in trial NCT05745883?
The interventions under investigation include: Placebo (DRUG), DISC-0974 (DRUG).
Who is sponsoring clinical trial NCT05745883?
This trial is sponsored by Disc Medicine, which has 9 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05745883 being conducted?
This trial has 13 study locations across California, Colorado, Florida, Georgia, Idaho. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Kidney Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05745883's enrollment target sits among peer trials
50 54th of 73 higher than 19 of 73 other Chronic Kidney Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Kidney Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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