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NCT05985486 · ClinicalTrials.gov registry record · NA
Brain Outcomes With Lifestyle Change in Down Syndrome
A NA study of Obesity and Alzheimer Disease, sponsored by University of Kansas Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 81
- Enrollment target
- 1
- Study location
NCT05985486: Recruiting NA study of Obesity and Alzheimer Disease, sponsored by University of Kansas Medical Center.
NCT05985486 is a NA study of Obesity and Alzheimer Disease that is actively recruiting participants, run by University of Kansas Medical Center. The registered enrollment target is 81 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05985486, a NA study of Obesity and Alzheimer Disease, is actively recruiting participants, sponsored by University of Kansas Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 81 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to determine if weight loss or changes in dietary intake can help prevent of delay adults with Down syndrome from developing Alzheimer's Disease Adults with Down syndrome without dementia will be randomized to either a weight loss group or a general health education control group. The weight loss group will be asked to follow a reduced energy diet, attend monthly education sessions delivered remotely and self-monitor diet and body weight using commercially available web-based applications. The control group will be asked to attend remotely delivered monthly education sessions on general health education topics. All participants will come to the University of Kansas Medical Center, 3 times across 12 months for a blood draw, cognitive testing, a MRI, assessment of height and weight, and assessment of diet intake.
Primary Outcome
Examines the amount of amyloid beta in a person's brain, measured by a blood draw.
Conditions Studied
Interventions
- BEHAVIORAL Diet
- BEHAVIORAL Health Education
Study Locations (1)
Kansas
- University of Kansas Medical Center - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 81 participants |
| Start Date | 2024-10-22 |
| Est. Completion | 2027-09-30 |
| Phase | NA |
What NCT05985486 shows while recruiting
NCT05985486 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 81 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (90% lower).
The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Diet is the first listed.
NCT05985486 reports a single indexed study location in Kansas.
Frequently Asked Questions
What is clinical trial NCT05985486 about?
NCT05985486 is a clinical study titled "Brain Outcomes With Lifestyle Change in Down Syndrome". The goal of this study is to determine if weight loss or changes in dietary intake can help prevent of delay adults with Down syndrome from developing Alzheimer's Disease Adults with Down syndrome without dementia will be randomized to either a weight loss group or a general health education contro...
What is the current status of trial NCT05985486?
This trial is currently recruiting. It is a NA study. The enrollment target is 81 participants. The study started on 2024-10-22. Estimated completion is 2027-09-30.
What conditions does trial NCT05985486 study?
This clinical trial studies the following conditions: Obesity, Alzheimer Disease, Down Syndrome.
What interventions are being tested in trial NCT05985486?
The interventions under investigation include: Diet (BEHAVIORAL), Health Education (BEHAVIORAL).
Who is sponsoring clinical trial NCT05985486?
This trial is sponsored by University of Kansas Medical Center, which has 408 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05985486 being conducted?
This trial has 1 study location across Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05985486's enrollment target sits among peer trials
81 543rd of 1053 higher than 509 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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