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NCT05700682 · ClinicalTrials.gov registry record

Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee

A clinical trial of Osteoarthritis, Knee and Pain, Chronic, sponsored by Palo Alto Veterans Institute for Research.

Recruiting
Registry status
120
Enrollment target
1
Study location

NCT05700682 is a study of Osteoarthritis, Knee and Pain, Chronic that is actively recruiting participants, run by Palo Alto Veterans Institute for Research. The registered enrollment target is 120 participants, below the 579-participant average among 91 other Osteoarthritis, Knee trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05700682, a study of Osteoarthritis, Knee and Pain, Chronic, is actively recruiting participants, sponsored by Palo Alto Veterans Institute for Research.

RECRUITING
Registry status
120 participants
Enrollment target
1
Study location

Study Summary

In this work the investigators will study the relationship between chronic musculoskeletal pain and abnormal blood flow (neovascularity) around the shoulder, hip and knee. Veterans with as history of chronic shoulder, hip or knee pain and mild/moderate joint degenerative changes will be potential study subjects. Blood flow around joints will be evaluated using perfusion magnetic resonance imaging (MRI). Participants with demonstrably abnormal blood flow around their painful joint will be eligible for enrollment in a pilot study of joint embolization to treat their pain. Participants who choose to not undergo treatment will be re-assessed with MRI after one year to characterize the natural history of joint neovascularity and its relationship to pain.

Interventions

  • DEVICE Shoulder/Hip/Knee Embolization with Embozene Microspheres

Study Locations (1)

California

  • VA Palo Alto Healthcare System - Palo Alto

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2023-07-15
Est. Completion 2026-08-01

What the Registry Record Tells You About NCT05700682

The ClinicalTrials.gov registry entry for NCT05700682 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 579-participant average among 91 other Osteoarthritis, Knee trials with a reported enrollment target (79% lower). The listed sponsor is Palo Alto Veterans Institute for Research, which has 35 total studies on file at ClinicalTrials.gov.

The record links to 7 conditions, with Osteoarthritis, Knee appearing as the primary indexed condition, and to 1 intervention - of which Shoulder/Hip/Knee Embolization with Embozene Microspheres is the first listed.

NCT05700682 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT05700682 about?

NCT05700682 is a clinical study titled "Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee". In this work the investigators will study the relationship between chronic musculoskeletal pain and abnormal blood flow (neovascularity) around the shoulder, hip and knee. Veterans with as history of chronic shoulder, hip or knee pain and mild/moderate joint degenerative changes will be potential st...

What is the current status of trial NCT05700682?

This trial is currently recruiting. The enrollment target is 120 participants. The study started on 2023-07-15. Estimated completion is 2026-08-01.

What conditions does trial NCT05700682 study?

This clinical trial studies the following conditions: Osteoarthritis, Knee, Pain, Chronic, Osteoarthritis, Hip, Synovitis, Osteo Arthritis Shoulders.

What interventions are being tested in trial NCT05700682?

The interventions under investigation include: Shoulder/Hip/Knee Embolization with Embozene Microspheres (DEVICE).

Who is sponsoring clinical trial NCT05700682?

This trial is sponsored by Palo Alto Veterans Institute for Research, which has 35 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05700682 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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