Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05700682 · ClinicalTrials.gov registry record
Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee
A clinical trial of Osteoarthritis, Knee and Pain, Chronic, sponsored by Palo Alto Veterans Institute for Research.
- Recruiting
- Registry status
- 120
- Enrollment target
- 1
- Study location
NCT05700682: Recruiting study of Osteoarthritis, Knee and Pain, Chronic, sponsored by Palo Alto Veterans Institute for Research.
NCT05700682 is a study of Osteoarthritis, Knee and Pain, Chronic that is actively recruiting participants, run by Palo Alto Veterans Institute for Research. The registered enrollment target is 120 participants, below the 497-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05700682, a study of Osteoarthritis, Knee and Pain, Chronic, is actively recruiting participants, sponsored by Palo Alto Veterans Institute for Research.
- RECRUITING
- Registry status
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
In this work the investigators will study the relationship between chronic musculoskeletal pain and abnormal blood flow (neovascularity) around the shoulder, hip and knee. Veterans with as history of chronic shoulder, hip or knee pain and mild/moderate joint degenerative changes will be potential study subjects. Blood flow around joints will be evaluated using perfusion magnetic resonance imaging (MRI). Participants with demonstrably abnormal blood flow around their painful joint will be eligible for enrollment in a pilot study of joint embolization to treat their pain. Participants who choose to not undergo treatment will be re-assessed with MRI after one year to characterize the natural history of joint neovascularity and its relationship to pain.
Primary Outcome
Composite WOMAC survey score
Conditions Studied
Interventions
- DEVICE Shoulder/Hip/Knee Embolization with Embozene Microspheres
Study Locations (1)
California
- VA Palo Alto Healthcare System - Palo Alto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2023-07-15 |
| Est. Completion | 2026-08-01 |
What NCT05700682 shows while recruiting
NCT05700682 is an observational study that tracks outcomes without assigning an intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 497-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (76% lower).
The record links to 7 conditions, with Osteoarthritis, Knee appearing as the primary indexed condition, and to 1 intervention - of which Shoulder/Hip/Knee Embolization with Embozene Microspheres is the first listed.
NCT05700682 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05700682 about?
NCT05700682 is a clinical study titled "Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee". In this work the investigators will study the relationship between chronic musculoskeletal pain and abnormal blood flow (neovascularity) around the shoulder, hip and knee. Veterans with as history of chronic shoulder, hip or knee pain and mild/moderate joint degenerative changes will be potential st...
What is the current status of trial NCT05700682?
This trial is currently recruiting. The enrollment target is 120 participants. The study started on 2023-07-15. Estimated completion is 2026-08-01.
What conditions does trial NCT05700682 study?
This clinical trial studies the following conditions: Osteoarthritis, Knee, Pain, Chronic, Osteoarthritis, Hip, Synovitis, Osteo Arthritis Shoulders.
What interventions are being tested in trial NCT05700682?
The interventions under investigation include: Shoulder/Hip/Knee Embolization with Embozene Microspheres (DEVICE).
Who is sponsoring clinical trial NCT05700682?
This trial is sponsored by Palo Alto Veterans Institute for Research, which has 35 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05700682 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis, Knee
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05700682's enrollment target sits among peer trials
120 55th of 112 higher than 55 of 112 other Osteoarthritis, Knee trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis, Knee trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
A Hip Flexion Feedback System for Exercise Monitoring in Individuals With Osteoarthritis and Obesity
RECRUITING · Phase 1
-
A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain.
RECRUITING · Phase 3
-
Mobilizing Hispanics With Knee Osteoarthritis
RECRUITING · NA
-
Physica System Total Knee Replacement Registry Study
RECRUITING · NA
-
The Osteoarthritis Prevention Study
RECRUITING · NA
-
Preventing Injured Knees From osteoArthritis: Severity Outcomes
RECRUITING · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01174108 · 120 participants · Phase 2
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells
- NCT01627301 · 120 participants · NA
Sympathetic Overactivity in Post-traumatic Stress Disorder
- NCT02025023 · 120 participants · Phase 3
Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study
- NCT02128906 · 120 participants · Phase 2
Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI