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NCT05699460 · ClinicalTrials.gov registry record

Pre-Gene Therapy Study in Parkinson's Disease and Multiple System Atrophy

A clinical trial of Parkinson's Disease and Multiple System Atrophy, sponsored by AskBio.

Active
Registry status
150
Enrollment target
11
Study locations

NCT05699460: Active study of Parkinson's Disease and Multiple System Atrophy, sponsored by AskBio.

NCT05699460 is a study of Parkinson's Disease and Multiple System Atrophy that is active but no longer recruiting, run by AskBio. The registered enrollment target is 150 participants, below the 634-participant average among 158 other Parkinson's Disease trials with a reported enrollment target (76% lower). The trial reports 11 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05699460, a study of Parkinson's Disease and Multiple System Atrophy, is active but no longer recruiting, sponsored by AskBio.

ACTIVE NOT RECRUITING
Registry status
150 participants
Enrollment target
11
Study locations

Study Summary

The objective of this study is to describe disease progression in study participants diagnosed with early Parkinson's Disease or Multiple System Atrophy - Parkinsonian Type up to 18 months as delineated by clinical and biochemical parameters.

Primary Outcome

Change from baseline in the MDS-UPDRS. The MDS-UPDRS contains 4 subscales: Part I, non-motor aspects of experiences of daily living (13 items); Part II, motor aspects of experiences of daily living (13 items); Part III, motor examination (33 scores based on 18 items); Part IV, motor complications (6 items). The rating for each item, or sub-item, is from 0 (normal) to 4 (severe). The total score for each Part is obtained from the sum of the corresponding item scores.

Conditions Studied

Parkinson's Disease Multiple System Atrophy Multiple System Atrophy, Parkinson Variant

Interventions

  • OTHER This is an observational study.

Study Locations (11)

Other

  • Specjalistyczna Praktyka Lekarska, Prof. Grzegorz Opala - Katowice
  • Mazowiecki Szpital Bródnowski w Warszawie, Oddział Neurologii - Warsaw
  • Samodzielny Publiczny Szpital Kliniczny im. prof. Witolda Orłowskiego, Oddział Neurologii i Epileptologii - Warsaw

California

  • University of California Irvine - Irvine

Florida

  • Parkinson's Disease and Movement Disorders Center of Boca Raton - Boca Raton

Massachusetts

  • Massachusetts General Hospital - Boston

Michigan

  • Quest Research Institute - Farmington Hills

Ohio

  • Ohio Health Research Institute - Columbus

Oregon

  • OHSU Parkinson Center & Movement Disorders Program - Portland

Tennessee

  • Vanderbilt University Medical Center - Nashville

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2022-09-29
Est. Completion 2025-11
AskBio

8 total trials

What the registry record for NCT05699460 still lists

NCT05699460 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 634-participant average among 158 other Parkinson's Disease trials with a reported enrollment target (76% lower).

The record links to 3 conditions, with Parkinson's Disease appearing as the primary indexed condition, and to 1 intervention - of which This is an observational study. is the first listed.

NCT05699460 lists 11 locations in 9 states (Other, California, Florida).

Frequently Asked Questions

What is clinical trial NCT05699460 about?

NCT05699460 is a clinical study titled "Pre-Gene Therapy Study in Parkinson's Disease and Multiple System Atrophy". The objective of this study is to describe disease progression in study participants diagnosed with early Parkinson's Disease or Multiple System Atrophy - Parkinsonian Type up to 18 months as delineated by clinical and biochemical parameters.

What is the current status of trial NCT05699460?

This trial is currently active not recruiting. The enrollment target is 150 participants. The study started on 2022-09-29. Estimated completion is 2025-11.

What conditions does trial NCT05699460 study?

This clinical trial studies the following conditions: Parkinson's Disease, Multiple System Atrophy, Multiple System Atrophy, Parkinson Variant.

What interventions are being tested in trial NCT05699460?

The interventions under investigation include: This is an observational study. (OTHER).

Who is sponsoring clinical trial NCT05699460?

This trial is sponsored by AskBio, which has 8 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05699460 being conducted?

This trial has 11 study locations across California, Florida, Massachusetts, Michigan, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Parkinson's Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05699460's enrollment target sits among peer trials

150 43rd of 158 higher than 115 of 158 other Parkinson's Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Parkinson's Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT05699460, the US trial registry maintained by the National Library of Medicine. NCT05699460 (mid enrollment · multi site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.