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NCT05660772 · ClinicalTrials.gov registry record · Phase 3
Microfragmented Adipose Tissue Compared to Corticosteroid Injection for the Treatment of Knee Osteoarthritis
A Phase 3 study of Osteoarthritis, Knee and Knee Osteoarthritis, sponsored by Lipogems International spa.
- Completed
- Registry status
- Phase 3
- Development phase
- 173
- Enrollment target
- 18
- Study locations
NCT05660772: Completed Phase 3 study of Osteoarthritis, Knee and Knee Osteoarthritis, sponsored by Lipogems International spa.
NCT05660772 is a Phase 3 study of Osteoarthritis, Knee and Knee Osteoarthritis that has completed, run by Lipogems International spa. The registered enrollment target is 173 participants, below the 496-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (65% lower). The trial reports 18 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05660772, a Phase 3 study of Osteoarthritis, Knee and Knee Osteoarthritis, has completed, sponsored by Lipogems International spa.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 173 participants
- Enrollment target
- 18
- Study locations
Study Summary
The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus corticosteroid injection for the treatment of pain and function associated with K/L grade 2/3 knee Osteoarthritis. Participants will receive an injection of MFat or a corticosteroid.
Primary Outcome
The change from baseline to Month 12 for the Western Ontario and McMaster Universities Osteoarthritis Index pain (WOMAC-A) subscale score (superiority); Scale = 0-100, where 100 is extreme pain
Conditions Studied
Interventions
- DRUG Corticosteroid
- DEVICE Microfragmented Adipose Tissue
Study Locations (18)
Texas
- All American Ortho - Houston
- Texas Center for Cell Therapy and Research, LLC - San Antonio
- San Antonio Orthopedics - San Antonio
California
- CORE Orthopaedic Center - Encinitas
- Stanford University - Redwood City
Georgia
- Pinnacle Trials, Inc - Atlanta
- Emory University - Brookhaven
New York
- Northwell Health - New York
- Columbia University - Tarrytown
Ohio
- Cincinnati Sports Medicine and Orthopaedic Center - Cincinnati
- Ohio Health Research Institute - Columbus
Florida
- Andrews Research & Education Foundation - Gulf Breeze
Iowa
- University of Iowa Sports Medicine - Iowa City
Maryland
- Regenerative Orthopedics and Sports Medicine (ROSM) - North Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 173 participants |
| Start Date | 2022-12-30 |
| Est. Completion | 2025-04-09 |
| Phase | Phase 3 |
What the finished NCT05660772 record still lists
NCT05660772 is an interventional study that assigns participants to a tested intervention. The registered 173 participants enrollment target is mid-sized for trials with a published cap, below the 496-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (65% lower).
The record links to 2 conditions, with Osteoarthritis, Knee appearing as the primary indexed condition, and to 2 interventions - of which Corticosteroid is the first listed.
NCT05660772 lists 18 locations in 12 states (Texas, California, Georgia).
Frequently Asked Questions
What is clinical trial NCT05660772 about?
NCT05660772 is a clinical study titled "Microfragmented Adipose Tissue Compared to Corticosteroid Injection for the Treatment of Knee Osteoarthritis". The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus corticosteroid injection for the treatment of pain and function associated with K/L grade 2/3 knee Osteoarthritis. Participants will receive an injection of MFat or a corticoste...
What is the current status of trial NCT05660772?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 173 participants. The study started on 2022-12-30. Estimated completion is 2025-04-09.
What conditions does trial NCT05660772 study?
This clinical trial studies the following conditions: Osteoarthritis, Knee, Knee Osteoarthritis.
What interventions are being tested in trial NCT05660772?
The interventions under investigation include: Corticosteroid (DRUG), Microfragmented Adipose Tissue (DEVICE).
Who is sponsoring clinical trial NCT05660772?
This trial is sponsored by Lipogems International spa, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05660772 being conducted?
This trial has 18 study locations across California, Florida, Georgia, Iowa, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis, Knee
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05660772's enrollment target sits among peer trials
173 39th of 112 higher than 73 of 112 other Osteoarthritis, Knee trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis, Knee trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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