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COMPLETED Phase 3

Microfragmented Adipose Tissue Compared to Corticosteroid Injection for the Treatment of Knee Osteoarthritis

NCT05660772 · View on ClinicalTrials.gov ↗

Study Summary

The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus corticosteroid injection for the treatment of pain and function associated with K/L grade 2/3 knee Osteoarthritis. Participants will receive an injection of MFat or a corticosteroid.

Interventions

  • DRUG Corticosteroid
  • DEVICE Microfragmented Adipose Tissue

Study Locations (18)

Texas

  • All American Ortho — Houston
  • Texas Center for Cell Therapy and Research, LLC — San Antonio
  • San Antonio Orthopedics — San Antonio

California

  • CORE Orthopaedic Center — Encinitas
  • Stanford University — Redwood City

Georgia

  • Pinnacle Trials, Inc — Atlanta
  • Emory University — Brookhaven

New York

  • Northwell Health — New York
  • Columbia University — Tarrytown

Ohio

  • Cincinnati Sports Medicine and Orthopaedic Center — Cincinnati
  • Ohio Health Research Institute — Columbus

Florida

  • Andrews Research & Education Foundation — Gulf Breeze

Iowa

  • University of Iowa Sports Medicine — Iowa City

Maryland

  • Regenerative Orthopedics and Sports Medicine (ROSM) — North Bethesda

Trial Details

FieldValue
Enrollment Target 173 participants
Start Date 2022-12-30
Est. Completion 2025-04-09
Phase Phase 3

Sponsor

Lipogems International spa

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05660772

The ClinicalTrials.gov registry entry for NCT05660772 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 173 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Lipogems International spa, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Knee Osteoarthritis appearing as the primary indexed condition, and to 2 interventions — of which Corticosteroid is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05660772 reports 18 study locations spanning 12 distinct geographic areas — top geographies include Texas, California, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05660772 about?

NCT05660772 is a clinical study titled "Microfragmented Adipose Tissue Compared to Corticosteroid Injection for the Treatment of Knee Osteoarthritis". The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus corticosteroid injection for the treatment of pain and function associated with K/L grade 2/3 knee Osteoarthritis. Participants will receive an injection of MFat or a corticoste...

What is the current status of trial NCT05660772?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 173 participants. The study started on 2022-12-30. Estimated completion is 2025-04-09.

What conditions does trial NCT05660772 study?

This clinical trial studies the following conditions: Knee Osteoarthritis, Osteo Arthritis Knee. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05660772?

The interventions under investigation include: Corticosteroid (DRUG), Microfragmented Adipose Tissue (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05660772?

This trial is sponsored by Lipogems International spa, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05660772 being conducted?

This trial has 18 study locations across California, Florida, Georgia, Iowa, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial