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NCT05567796 · ClinicalTrials.gov registry record · Phase 3

A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight

A Phase 3 study of Obesity, sponsored by Novo Nordisk A/S.

Active
Registry status
Phase 3
Development phase
3,400
Enrollment target
20
Study locations

NCT05567796: Active Phase 3 study of Obesity, sponsored by Novo Nordisk A/S.

NCT05567796 is a Phase 3 study of Obesity that is active but no longer recruiting, run by Novo Nordisk A/S. The registered enrollment target is 3,400 participants, above the 816-participant average among 1,053 other Obesity trials with a reported enrollment target (317% higher). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05567796, a Phase 3 study of Obesity, is active but no longer recruiting, sponsored by Novo Nordisk A/S.

ACTIVE NOT RECRUITING
Registry status
Phase 3
Development phase
3,400 participants
Enrollment target
20
Study locations

Study Summary

This study has 2 parts: First part is the main study and second part is the extension study. During the main study participants will receive 1 of 4 study medicines. If participants continue in the extension study, they will not receive any study medicine during the extension. The main study will look at how well CagriSema helps participants with excess body weight lose weight compared to a "dummy" medicine and 2 other medicines, cagrilintide and semaglutide. Participants will either get CagriSema, cagrilintide,semaglutide or "dummy" medicine. Which treatment participants get is decided by chance. They will take one injection once a week. The study medicine is injected briefly with a thin needle, typically in the stomach, thighs or upper arms. Extension study: After the main study, not all participants will continue in the extension study. The study staff will tell the participant if they will continue or not into the extension study. In the extension study we will look at what happens to the participant's body weight and diseases related to excess body weight after the participant stops taking the study medicine. The main study will last for about 1½ years and the extension study will last for another 2 years.

Conditions Studied

Interventions

  • DRUG Semaglutide
  • DRUG Cagrilintide
  • DRUG Placebo cagrilintide
  • DRUG Placebo semaglutide

Study Locations (20)

Florida

  • Northeast Research Institute - Fleming Island
  • South Broward Research LLC - Miramar
  • Clinical Neuroscience Solution - Orlando
  • Florida Inst For Clin Res - Orlando
  • Clinical Trial Res Assoc,Inc - Plantation

Illinois

  • Great Lakes Clinical Trials - Chicago
  • Endeavor Health - Skokie
  • Evanston Premier Hlthcr Res - Skokie

California

  • Velocity Clin Res Los Angeles - Los Angeles
  • Velocity Clin Res Wstlke - Los Angeles

Colorado

  • Univ of Colorado at Denver - Aurora
  • New West Physicians,Inc. - Golden

New York

  • Velocity Clinical Research Binghamton - Binghamton
  • Comprehensive Weight Ctrl Prog - New York

Alabama

  • Univ of Alabama Birmingham - Birmingham

Georgia

  • Hope Clin Res & Wellness - Conyers

Hawaii

  • East West Med Res Inst - Honolulu

Trial Details

FieldValue
Enrollment Target 3,400 participants
Start Date 2022-11-01
Est. Completion 2026-10-19
Phase Phase 3

Sponsor

Novo Nordisk A/S

431 total trials

What the Registry Record Tells You About NCT05567796

The ClinicalTrials.gov registry entry for NCT05567796 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 3,400 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 816-participant average among 1,053 other Obesity trials with a reported enrollment target (317% higher). The listed sponsor is Novo Nordisk A/S, which has 431 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 4 interventions - of which Semaglutide is the first listed.

NCT05567796 reports 20 study locations spanning 11 distinct geographic areas - top geographies include Florida, Illinois, California.

Frequently Asked Questions

What is clinical trial NCT05567796 about?

NCT05567796 is a clinical study titled "A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight". This study has 2 parts: First part is the main study and second part is the extension study. During the main study participants will receive 1 of 4 study medicines. If participants continue in the extension study, they will not receive any study medicine during the extension. The main study will loo...

What is the current status of trial NCT05567796?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 3,400 participants. The study started on 2022-11-01. Estimated completion is 2026-10-19.

What conditions does trial NCT05567796 study?

This clinical trial studies the following conditions: Obesity.

What interventions are being tested in trial NCT05567796?

The interventions under investigation include: Semaglutide (DRUG), Cagrilintide (DRUG), Placebo cagrilintide (DRUG), Placebo semaglutide (DRUG).

Who is sponsoring clinical trial NCT05567796?

This trial is sponsored by Novo Nordisk A/S, which has 431 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05567796 being conducted?

This trial has 20 study locations across Alabama, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.