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NCT06672575 · ClinicalTrials.gov registry record · Phase 1

A Phase I/II Study of IVONESCIMAB in Recurrent Glioblastoma

A Phase 1 study of Glioblastoma, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 1
Development phase
45
Enrollment target
2
Study locations

NCT06672575 is a Phase 1 study of Glioblastoma that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 45 participants, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (59% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT06672575, a Phase 1 study of Glioblastoma, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 1
Development phase
45 participants
Enrollment target
2
Study locations

Study Summary

The goal of Phase 1 of this clinical research study is to find the highest tolerable dose and the recommended Phase 2 dose of ivonescimab that can be given to patients who have recurrent glioblastoma. The goal of Phase 2 of this clinical research study is to learn if the recommended Phase 2 dose of ivonescimab found in Phase 1 can help to control the disease.

Conditions Studied

Glioblastoma

Interventions

  • DRUG Ivonescimab

Study Locations (2)

Texas

  • The University of Texas M. D. Anderson Cancer Center - Houston
  • The University of Texas MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2025-01-30
Est. Completion 2030-01-31
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

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What the Registry Record Tells You About NCT06672575

The ClinicalTrials.gov registry entry for NCT06672575 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (59% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Glioblastoma appearing as the primary indexed condition, and to 1 intervention - of which Ivonescimab is the first listed.

NCT06672575 reports 2 study locations spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT06672575 about?

NCT06672575 is a clinical study titled "A Phase I/II Study of IVONESCIMAB in Recurrent Glioblastoma". The goal of Phase 1 of this clinical research study is to find the highest tolerable dose and the recommended Phase 2 dose of ivonescimab that can be given to patients who have recurrent glioblastoma. The goal of Phase 2 of this clinical research study is to learn if the recommended Phase 2 dose of...

What is the current status of trial NCT06672575?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 45 participants. The study started on 2025-01-30. Estimated completion is 2030-01-31.

What conditions does trial NCT06672575 study?

This clinical trial studies the following conditions: Glioblastoma.

What interventions are being tested in trial NCT06672575?

The interventions under investigation include: Ivonescimab (DRUG).

Who is sponsoring clinical trial NCT06672575?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06672575 being conducted?

This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.