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NCT05556512 · ClinicalTrials.gov registry record · Phase 3
A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity
A Phase 3 study of Obesity and Overweight, sponsored by Eli Lilly and Company.
- Active
- Registry status
- Phase 3
- Development phase
- 15,374
- Enrollment target
- 20
- Study locations
NCT05556512: Active Phase 3 study of Obesity and Overweight, sponsored by Eli Lilly and Company.
NCT05556512 is a Phase 3 study of Obesity and Overweight that is active but no longer recruiting, run by Eli Lilly and Company. The registered enrollment target is 15,374 participants, above the 804-participant average among 1,053 other Obesity trials with a reported enrollment target (1812% higher). The trial reports 20 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05556512, a Phase 3 study of Obesity and Overweight, is active but no longer recruiting, sponsored by Eli Lilly and Company.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 15,374 participants
- Enrollment target
- 20
- Study locations
Study Summary
This study will investigate the effect of tirzepatide on the reduction of morbidity and mortality in adults living with obesity and provide additional evidence for the potential clinical benefits of tirzepatide in this population.
Primary Outcome
Time to first occurrence of any component event of composite, all-cause death, nonfatal MI, nonfatal stroke, coronary revascularization, or heart failure events that results in hospitalization or urgent visits.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Tirzepatide
Study Locations (20)
California
- Smart Cures Clinical Research - Anaheim
- Kidney & Hypertension Center - Apple Valley - Apple Valley
- Hope Clinical Research, Inc. - Canoga Park
- John Muir Physician Network Research Center - Concord
- Neighborhood Healthcare Institute of Health - Escondido
- HB Clinical Trials - Fountain Valley - Fountain Valley
- Valiance Clinical Research - Huntington Park
- Scripps Whittier Diabetes Institute - La Jolla
- Velocity Clinical Research, San Diego - La Mesa
- First Valley Medical Group - Lancaster
- Long Beach Clinical Trials - Long Beach
- Infinity Clinical Research - Norco - Norco
- California Medical Research Associates - Northridge
- Diabetes Associates Medical Group - Orange
- University of California Irvine Medical Center - Orange
Arizona
- Prime Medical Group, LLC dba Gilbert Center for Family Medicine, LLC - Gilbert
- Aventiv Research - Mesa
- Elite Clinical Studies - Phoenix
- Pima Heart - Tucson
Arkansas
- KLR Business Group, Inc. dba Arkansas Clinical Research - Little Rock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15,374 participants |
| Start Date | 2022-10-11 |
| Est. Completion | 2027-10 |
| Phase | Phase 3 |
What the registry record for NCT05556512 still lists
NCT05556512 is an interventional study that assigns participants to a tested intervention. Its 15,374 participants enrollment target places it among the larger protocols in the corpus, above the 804-participant average among 1,053 other Obesity trials with a reported enrollment target (1812% higher).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05556512 names 20 study sites across 3 states, led by California, Arizona, Arkansas.
Frequently Asked Questions
What is clinical trial NCT05556512 about?
NCT05556512 is a clinical study titled "A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity". This study will investigate the effect of tirzepatide on the reduction of morbidity and mortality in adults living with obesity and provide additional evidence for the potential clinical benefits of tirzepatide in this population.
What is the current status of trial NCT05556512?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 15,374 participants. The study started on 2022-10-11. Estimated completion is 2027-10.
What conditions does trial NCT05556512 study?
This clinical trial studies the following conditions: Obesity, Overweight.
What interventions are being tested in trial NCT05556512?
The interventions under investigation include: Placebo (DRUG), Tirzepatide (DRUG).
Who is sponsoring clinical trial NCT05556512?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05556512 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05556512's enrollment target sits among peer trials
15,374 5th of 1053 higher than 1,049 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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