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NCT05548660 · ClinicalTrials.gov registry record · NA
Pharmacogenetic-guided Choice of Post-surgery Analgesics
A NA study of Post Operative Pain and Acute Pain, sponsored by University of Pennsylvania.
- Completed
- Registry status
- NA
- Development phase
- 112
- Enrollment target
- 1
- Study location
NCT05548660 is a NA study of Post Operative Pain and Acute Pain that has completed, run by University of Pennsylvania. The registered enrollment target is 112 participants, below the 234-participant average among 56 other Post Operative Pain trials with a reported enrollment target (52% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05548660, a NA study of Post Operative Pain and Acute Pain, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- NA
- Development phase
- 112 participants
- Enrollment target
- 1
- Study location
Study Summary
Pharmacogenomics (PGx) is the study of how genes affect a person's response to drugs. PGx testing for certain genes can help predict the risk of side effects or therapeutic failure from analgesics. Testing is not regularly performed in clinical practice due to long wait times for results and challenges with integrating test results in the electronic health record. Investigators leading this study hope to find out if providing surgeons with the ability to order a PGx test and electronically receive results with dosing recommendations will increase the use of these tests to guide analgesic choice and improve patient outcomes. This is a prospective, two-arm randomized implementation study. Eligible participants will be randomly assigned to receive genotype-guided analgesic selection (intervention arm) or usual care (control arm). Both cohorts will undergo pharmacogenetic testing at the time of consenting. The investigators will primarily measure the feasibility of using this test to guide analgesic selection.
Conditions Studied
Interventions
- OTHER Pharmacogenetic testing
- OTHER Pharmacist note with genotype-guided analgesic recommendations
- OTHER Pharmacist detailed note with genotype-guided recommendations per CPIC guidelines
Study Locations (1)
Pennsylvania
- University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 112 participants |
| Start Date | 2022-10-13 |
| Est. Completion | 2025-02-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05548660
The ClinicalTrials.gov registry entry for NCT05548660 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 112 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 234-participant average among 56 other Post Operative Pain trials with a reported enrollment target (52% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Post Operative Pain appearing as the primary indexed condition, and to 3 interventions - of which Pharmacogenetic testing is the first listed.
NCT05548660 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05548660 about?
NCT05548660 is a clinical study titled "Pharmacogenetic-guided Choice of Post-surgery Analgesics". Pharmacogenomics (PGx) is the study of how genes affect a person's response to drugs. PGx testing for certain genes can help predict the risk of side effects or therapeutic failure from analgesics. Testing is not regularly performed in clinical practice due to long wait times for results and challen...
What is the current status of trial NCT05548660?
This trial is currently completed. It is a NA study. The enrollment target is 112 participants. The study started on 2022-10-13. Estimated completion is 2025-02-01.
What conditions does trial NCT05548660 study?
This clinical trial studies the following conditions: Post Operative Pain, Acute Pain.
What interventions are being tested in trial NCT05548660?
The interventions under investigation include: Pharmacogenetic testing (OTHER), Pharmacist note with genotype-guided analgesic recommendations (OTHER), Pharmacist detailed note with genotype-guided recommendations per CPIC guidelines (OTHER).
Who is sponsoring clinical trial NCT05548660?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05548660 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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