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NCT05544136 · ClinicalTrials.gov registry record · Phase 2

A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer

A Phase 2 study of Head and Neck Cancer and Head and Neck Squamous Cell Carcinoma, sponsored by Memorial Sloan Kettering Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
12
Enrollment target
6
Study locations

NCT05544136 is a Phase 2 study of Head and Neck Cancer and Head and Neck Squamous Cell Carcinoma that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 12 participants, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (95% lower). The trial reports 6 study locations across 2 states.

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The verdict

NCT05544136, a Phase 2 study of Head and Neck Cancer and Head and Neck Squamous Cell Carcinoma, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
12 participants
Enrollment target
6
Study locations

Study Summary

The purpose of this study is to test the treatment approach of de-escalated radiation and chemotherapy followed by a planned neck dissection surgery in people with head and neck cancer. The study will look at how effective the treatment approach is against participants' cancer.

Conditions Studied

Head and Neck Cancer Head and Neck Squamous Cell Carcinoma Head and Neck Carcinoma Head and Neck Neoplasms

Interventions

  • DRUG Carboplatin
  • DIAGNOSTIC_TEST 18F-FMISO PET/CT scan
  • RADIATION Chemoradiation therapy

Study Locations (6)

New Jersey

  • Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities) - Basking Ridge
  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities) - Middletown
  • Memorial Sloan Kettering Bergen (Limited Protocol Activities) - Montvale

New York

  • Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Limited protocol activities) - Commack
  • Memorial Sloan Kettering Westchester (Limited Protocol Activities) - Harrison
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities) - New York

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2022-09-12
Est. Completion 2027-03-12
Phase Phase 2

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05544136

The ClinicalTrials.gov registry entry for NCT05544136 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (95% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 3 interventions - of which Carboplatin is the first listed.

NCT05544136 reports 6 study locations spanning 2 distinct geographic areas - top geographies include New Jersey, New York.

Frequently Asked Questions

What is clinical trial NCT05544136 about?

NCT05544136 is a clinical study titled "A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer". The purpose of this study is to test the treatment approach of de-escalated radiation and chemotherapy followed by a planned neck dissection surgery in people with head and neck cancer. The study will look at how effective the treatment approach is against participants' cancer.

What is the current status of trial NCT05544136?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2022-09-12. Estimated completion is 2027-03-12.

What conditions does trial NCT05544136 study?

This clinical trial studies the following conditions: Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Head and Neck Carcinoma, Head and Neck Neoplasms.

What interventions are being tested in trial NCT05544136?

The interventions under investigation include: Carboplatin (DRUG), 18F-FMISO PET/CT scan (DIAGNOSTIC_TEST), Chemoradiation therapy (RADIATION).

Who is sponsoring clinical trial NCT05544136?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05544136 being conducted?

This trial has 6 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.