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NCT05517811 · ClinicalTrials.gov registry record
Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection
A clinical trial of Colorectal Cancer and Esophageal Cancer, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- 400
- Enrollment target
- 1
- Study location
NCT05517811: Recruiting study of Colorectal Cancer and Esophageal Cancer, sponsored by University of Colorado, Denver.
NCT05517811 is a study of Colorectal Cancer and Esophageal Cancer that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 400 participants, below the 1,544-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05517811, a study of Colorectal Cancer and Esophageal Cancer, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- 400 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and lung adenocarcinoma can serve as biomarkers for oncologic disease burden, cancer recurrence and overall survival as well as thrombotic and hemorrhagic post-operative complications. The investigators further hypothesize that there is histologic pathology correlates to pre-operative TEG abnormalities, and that it identifies patients with virulent tumor biology.
Primary Outcome
R time (minutes \~ coagulation factors), angle (degrees \~ fibrinogen function), MA (mm \~ platelets function), and LY30 (%\~ fibrinolysis) measured at baseline (initial presentation or time of diagnosis), after neoadjuvant chemotherapy (if applicable), pre-operatively (before the induction of general anesthesia), intra-operatively (after tumor removal), post-operative days 1, 3 and 5, and at routine follow up appointments at 2 weeks, 3 months, 6 months and 1 year after surgery.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST TEG indices
Study Locations (1)
Colorado
- University of Colorado Denver - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2022-06-26 |
| Est. Completion | 2028-07-31 |
What NCT05517811 shows while recruiting
NCT05517811 is an observational study that tracks outcomes without assigning an intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 1,544-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (74% lower).
The record links to 7 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 1 intervention - of which TEG indices is the first listed.
NCT05517811 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT05517811 about?
NCT05517811 is a clinical study titled "Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection". The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and lung adenocarcinoma can serve as biomarkers for oncologic disease burden, cancer recurrence and overall survival as well as thrombotic and h...
What is the current status of trial NCT05517811?
This trial is currently recruiting. The enrollment target is 400 participants. The study started on 2022-06-26. Estimated completion is 2028-07-31.
What conditions does trial NCT05517811 study?
This clinical trial studies the following conditions: Colorectal Cancer, Esophageal Cancer, Liver Cancer, Pancreas Cancer, Lung Adenocarcinoma.
What interventions are being tested in trial NCT05517811?
The interventions under investigation include: TEG indices (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05517811?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05517811 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Colorectal Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05517811's enrollment target sits among peer trials
400 93rd of 381 higher than 284 of 381 other Colorectal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Colorectal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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