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NCT05455086 · ClinicalTrials.gov registry record · NA
Free-Base Nicotine or Nicotine Salt e-Liquids in Current E-Cigarette Smokers, PeloPET Study
A NA study, sponsored by Ohio State University Comprehensive Cancer Center.
- Completed
- Registry status
- NA
- Development phase
- 21
- Enrollment target
NCT05455086: Completed NA study, sponsored by Ohio State University Comprehensive Cancer Center.
NCT05455086 is a NA study that has completed, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 21 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05455086, a NA study, has completed, sponsored by Ohio State University Comprehensive Cancer Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 21 participants
- Enrollment target
Study Summary
This clinical trial studies the effect of free-base compared with nicotine salt based e-liquids on electronic cigarette (EC) puffing behavior, abuse liability, and deposition and absorption of nicotine in the respiratory tract and rate of uptake in the brain in current EC smokers. The results from this study may provide much needed scientific information to public health officials and regulators.
Primary Outcome
Evaluate effect of nicotine form (free-base vs nicotine salt base) on nicotine absorption and distribution in the brain with total absorbed dose (TAD) of \[11C\]nicotine.
Interventions
- PROCEDURE Computed Tomography
- BEHAVIORAL Cigarette Smoking
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2022-03-23 |
| Est. Completion | 2023-06-26 |
| Phase | NA |
What the finished NCT05455086 record still lists
NCT05455086 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Computed Tomography is the first listed.
NCT05455086 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05455086 about?
NCT05455086 is a clinical study titled "Free-Base Nicotine or Nicotine Salt e-Liquids in Current E-Cigarette Smokers, PeloPET Study". This clinical trial studies the effect of free-base compared with nicotine salt based e-liquids on electronic cigarette (EC) puffing behavior, abuse liability, and deposition and absorption of nicotine in the respiratory tract and rate of uptake in the brain in current EC smokers. The results from t...
What is the current status of trial NCT05455086?
This trial is currently completed. It is a NA study. The enrollment target is 21 participants. The study started on 2022-03-23. Estimated completion is 2023-06-26.
What interventions are being tested in trial NCT05455086?
The interventions under investigation include: Computed Tomography (PROCEDURE), Cigarette Smoking (BEHAVIORAL).
Who is sponsoring clinical trial NCT05455086?
This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05455086's enrollment target sits among peer trials
21 1762nd of 2000 higher than 233 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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