Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 3 recruiting now early-phase tilt small index

Postural Tachycardia Syndrome (POTS): early-phase trial registry

3 of 4 indexed Postural Tachycardia Syndrome (POTS) trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #4,115 of 28,707 conditions by registered trial count.

4 US clinical trials · 3 currently recruiting · #4,115 of 28,707 conditions by registered trial count

Postural Tachycardia Syndrome (POTS): 4 US clinical trials tracked, 3 recruiting.

Postural Tachycardia Syndrome (POTS) is the subject of 4 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Vanderbilt University Medical Center, running 4 of these trials.

Enrollment posture brief

Registry condition postural-tachycardia-syndrome-pots

OPEN 3 | RECR 75% | LATE 0 | EARLY 2 | RANK #4115 | SPON 4

Nearest open-share peer: Activity, Motor (75% recruiting · 8 trials)

Ablation80%ACL Reconstruction80%Postural Tachycardia Syn (th…75%Abuse, Drug60%Acceptability60%
Open-enrollment share among volume-matched conditions near Postural Tachycardia Syndrome (POTS)

Postural Tachycardia Syndrome (POTS) lists 3 open slots (75% of 4 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Postural Tachycardia Syndrome (POTS) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Postural Tachycardia Syndrome (POTS) is recruiting above its size-band peers.

    3 of 4 indexed trials (75%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

Phase 22

Phase Distribution

PhaseTrial count
Phase 2 2

Top Sponsors

Named interventions

Most-linked intervention names on Postural Tachycardia Syndrome (POTS) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Evaluation of Forearm-Mediated Dilation Device
1 trials
Calf Blood Flow in Reactive Hyperemia (CBF-RH) Device
1 trials
Pulsitile Arterial Tonometry (PAT) Protocol Procedure
1 trials
To Measure Splanchnic venous capacitance after 28 days of Treatment with Placebo Diagnostic test
1 trials
To Measure Splanchnic venous capacitance after 28 days of Treatment with 2HOBA Diagnostic test
1 trials
To measure levels of circulating monocyte/ T cell doublets after 28 days of Placebo treatment Drug
1 trials
To measure levels of circulating monocyte/ T cell doublets after 28 days of 2 HOBA treatment Drug
1 trials
To Measure levels of circulating monocyte/ T cell doublets at Baseline Drug
1 trials

US sites by state

Facility locations filed on Postural Tachycardia Syndrome (POTS) trials. A trial with sites in several states counts in each.

Tennessee 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Postural Tachycardia Syndrome (POTS) page

4 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Postural Tachycardia Syndrome (POTS) condition card totals 4 registered trials; most-linked intervention Evaluation of Forearm-Mediated Dilation; top US site state Tennessee. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.