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NCT05393258 · ClinicalTrials.gov registry record · NA

Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas

A NA study of Astrocytoma and Glioma, Malignant, sponsored by Washington University School of Medicine.

Completed
Registry status
NA
Development phase
13
Enrollment target
1
Study location

NCT05393258 is a NA study of Astrocytoma and Glioma, Malignant that has completed, run by Washington University School of Medicine. The registered enrollment target is 13 participants, below the 49-participant average among 19 other Astrocytoma trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05393258, a NA study of Astrocytoma and Glioma, Malignant, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
NA
Development phase
13 participants
Enrollment target
1
Study location

Study Summary

This clinical trial studies the side effects of temporally-modulated pulsed radiation therapy (TMPRT) in patients with IDH-mutant gliomas who have previously received radiation therapy to the brain. TMPRT is a radiation technique in which radiation is delivered in multiple small doses on a specific timed interval, instead of delivering one large dose at one time. This technique may improve efficacy while reducing toxicity and improving patient quality of life.

Interventions

  • RADIATION temporally-modulated pulsed radiotherapy (TMPRT)

Study Locations (1)

Missouri

  • Washington University School of Medicine - St Louis

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2022-06-28
Est. Completion 2026-03-13
Phase NA

What the Registry Record Tells You About NCT05393258

The ClinicalTrials.gov registry entry for NCT05393258 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 13 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 49-participant average among 19 other Astrocytoma trials with a reported enrollment target (73% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Astrocytoma appearing as the primary indexed condition, and to 1 intervention - of which temporally-modulated pulsed radiotherapy (TMPRT) is the first listed.

NCT05393258 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.

Frequently Asked Questions

What is clinical trial NCT05393258 about?

NCT05393258 is a clinical study titled "Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas". This clinical trial studies the side effects of temporally-modulated pulsed radiation therapy (TMPRT) in patients with IDH-mutant gliomas who have previously received radiation therapy to the brain. TMPRT is a radiation technique in which radiation is delivered in multiple small doses on a specific ...

What is the current status of trial NCT05393258?

This trial is currently completed. It is a NA study. The enrollment target is 13 participants. The study started on 2022-06-28. Estimated completion is 2026-03-13.

What conditions does trial NCT05393258 study?

This clinical trial studies the following conditions: Astrocytoma, Glioma, Malignant, Oligodendroglioma, Adult.

What interventions are being tested in trial NCT05393258?

The interventions under investigation include: temporally-modulated pulsed radiotherapy (TMPRT) (RADIATION).

Who is sponsoring clinical trial NCT05393258?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05393258 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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