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2026 data Public-data reference. official source

Astrocytoma

Open-data reference.

20 US clinical trials · 10 currently recruiting

Active & Recent Trials

RECRUITING NA 112 participants

FearLess in NeuroOncology

Virginia Commonwealth University

NCT06989086

RECRUITING Phase 1 66 participants

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

Orbus Therapeutics

NCT05879367

RECRUITING Phase 2 60 participants

Study of Olutasidenib and Temozolomide in HGG

Rigel Pharmaceuticals

NCT06161974

RECRUITING Phase 2 55 participants

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

Stephen Bagley, MD, MSCE

NCT05345002

RECRUITING Phase 2 40 participants

Venous Thromboembolism Prevention in Outpatients With Glioma

University of Vermont Medical Center

NCT05683808

RECRUITING Phase 1 28 participants

Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

National Cancer Institute (NCI)

NCT06344130

RECRUITING Phase 1 24 participants

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

M.D. Anderson Cancer Center

NCT03911388

RECRUITING NA 20 participants

Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade Glioma

Columbia University

NCT06108206

RECRUITING Phase 1 18 participants

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

Henry Ford Health System

NCT05686798

RECRUITING Early Phase 1 12 participants

Implantable Microdevice In Primary Brain Tumors

Oliver Jonas

NCT04135807

ACTIVE NOT RECRUITING Phase 4 163 participants

Pediatric Long-Term Follow-up and Rollover Study

Novartis Pharmaceuticals

NCT03975829

ACTIVE NOT RECRUITING Phase 1 62 participants

A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2

Dana-Farber Cancer Institute

NCT03152318

ACTIVE NOT RECRUITING Phase 1 60 participants

Study of Vorasidenib and Pembrolizumab Combination in Recurrent or Progressive IDH-1 Mutant Glioma

Institut de Recherches Internationales Servier

NCT05484622

ACTIVE NOT RECRUITING Phase 1 60 participants

Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma

Northwestern University

NCT05236036

ACTIVE NOT RECRUITING NA 44 participants

Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma

University of California, San Francis

NCT03739372

ACTIVE NOT RECRUITING Phase 1 16 participants

Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma

Oblato

NCT05561374

ACTIVE NOT RECRUITING Phase 1 12 participants

A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma

James Markert, MD

NCT06614855

COMPLETED 55 participants

Qualitative, Qualitative, and Functional Studies Over the First Year in Measuring Immune System Response During the First Year of Therapy in Patients With Brain Tumors

Wake Forest University Health Sciences

NCT02747407

COMPLETED Phase 1 18 participants

Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors

Emory University

NCT01331135

COMPLETED NA 13 participants

Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas

Washington University School of Medicine

NCT05393258

Phase Distribution

PhaseTrial count
Early Phase 1 11
Phase 2 3
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Astrocytoma Trial Landscape

ClinicalTrials.gov lists 20 US studies indexed under Astrocytoma, and 10 of those are currently open to recruitment — roughly 50% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Astrocytoma shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 14 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Astrocytoma is led by James Markert, MD with 1 indexed trial, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 20 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Astrocytoma?

PlainTrial tracks 20 US clinical trials for Astrocytoma, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Astrocytoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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