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NCT04270591 · ClinicalTrials.gov registry record · Phase 1

Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer

A Phase 1 study of C-Met Exon 14 Mutation, sponsored by Haihe Biopharma Co..

Recruiting
Registry status
Phase 1
Development phase
183
Enrollment target
20
Study locations

NCT04270591 is a Phase 1 study of C-Met Exon 14 Mutation that is actively recruiting participants, run by Haihe Biopharma Co.. The registered enrollment target is 183 participants. The trial reports 20 study locations across 14 states.

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The verdict

NCT04270591, a Phase 1 study of C-Met Exon 14 Mutation, is actively recruiting participants, sponsored by Haihe Biopharma Co..

RECRUITING
Registry status
Phase 1
Development phase
183 participants
Enrollment target
20
Study locations

Study Summary

Indication:Patients with Advanced c-MET-positive Non-Small Cell Lung Cancer Phase Ib (China only): Approximately 90 patients Phase Ⅱ (globally): Approximately 78 evaluable patients; addition of at least 6 patients in Safety Run-in (US only)

Conditions Studied

Interventions

  • DRUG Glumetinib

Study Locations (20)

Beijing Municipality

  • Beijing Cancer Hospital - Beijing
  • Beijing Cancer Hospita - Beijing
  • Peking Union Medical College Hospital - Beijing

Kentucky

  • Norton Cancer Institute - Louisville
  • The Oncology Institute of Hope & Innovation - Louisville

Anhui

  • Anhui Province Hospital - Hefei
  • The Chest Hospital of Anhui Province - Hefei

Hubei

  • Hubei Cancer Hospital - Wuhan
  • Wuhan Union Hospital - Wuhan

Jiangsu

  • Jiangsu Cancer Hospital - Nanjing
  • Jiangsu Province People's Hospital - Nanjing

Fujian

  • Union Medical College Hospital Affiliated to Fujian Medical University - Fuzhou

Guangdong

  • The First Affiliated Hospital of Guangzhou Medical University - Guangzhou

Guangxi

  • Cancer Hospital Affiliated to Guangxi Medical University - Nanning

Trial Details

FieldValue
Enrollment Target 183 participants
Start Date 2019-07-15
Est. Completion 2023-12-30
Phase Phase 1

Sponsor

Haihe Biopharma Co.

4 total trials

What the Registry Record Tells You About NCT04270591

The ClinicalTrials.gov registry entry for NCT04270591 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 183 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Haihe Biopharma Co., which has 4 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with C-Met Exon 14 Mutation appearing as the primary indexed condition, and to 1 intervention - of which Glumetinib is the first listed.

NCT04270591 reports 20 study locations spanning 14 distinct geographic areas - top geographies include Beijing Municipality, Kentucky, Anhui.

Frequently Asked Questions

What is clinical trial NCT04270591 about?

NCT04270591 is a clinical study titled "Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer". Indication:Patients with Advanced c-MET-positive Non-Small Cell Lung Cancer Phase Ib (China only): Approximately 90 patients Phase Ⅱ (globally): Approximately 78 evaluable patients; addition of at least 6 patients in Safety Run-in (US only)

What is the current status of trial NCT04270591?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 183 participants. The study started on 2019-07-15. Estimated completion is 2023-12-30.

What conditions does trial NCT04270591 study?

This clinical trial studies the following conditions: C-Met Exon 14 Mutation.

What interventions are being tested in trial NCT04270591?

The interventions under investigation include: Glumetinib (DRUG).

Who is sponsoring clinical trial NCT04270591?

This trial is sponsored by Haihe Biopharma Co., which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04270591 being conducted?

This trial has 20 study locations across Kentucky, Anhui, Beijing Municipality, Fujian, Guangdong. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.