Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer
NCT04270591 · View on ClinicalTrials.gov ↗
Study Summary
Indication:Patients with Advanced c-MET-positive Non-Small Cell Lung Cancer Phase Ib (China only): Approximately 90 patients Phase Ⅱ (globally): Approximately 78 evaluable patients; addition of at least 6 patients in Safety Run-in (US only)
Conditions Studied
Interventions
- DRUG Glumetinib
Study Locations (20)
Beijing Municipality
- Beijing Cancer Hospital — Beijing
- Beijing Cancer Hospita — Beijing
- Peking Union Medical College Hospital — Beijing
Kentucky
- Norton Cancer Institute — Louisville
- The Oncology Institute of Hope & Innovation — Louisville
Anhui
- Anhui Province Hospital — Hefei
- The Chest Hospital of Anhui Province — Hefei
Hubei
- Hubei Cancer Hospital — Wuhan
- Wuhan Union Hospital — Wuhan
Jiangsu
- Jiangsu Cancer Hospital — Nanjing
- Jiangsu Province People's Hospital — Nanjing
Fujian
- Union Medical College Hospital Affiliated to Fujian Medical University — Fuzhou
Guangdong
- The First Affiliated Hospital of Guangzhou Medical University — Guangzhou
Guangxi
- Cancer Hospital Affiliated to Guangxi Medical University — Nanning
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 183 participants |
| Start Date | 2019-07-15 |
| Est. Completion | 2023-12-30 |
| Phase | Phase 1 |
Interested in This Trial?
Always speak with your doctor before enrolling in a clinical trial.
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04270591
The ClinicalTrials.gov registry entry for NCT04270591 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 183 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Haihe Biopharma Co., which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with C-Met Exon 14 Mutation appearing as the primary indexed condition, and to 1 intervention — of which Glumetinib is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04270591 reports 20 study locations spanning 14 distinct geographic areas — top geographies include Beijing Municipality, Kentucky, Anhui. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04270591 about?
NCT04270591 is a clinical study titled "Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer". Indication:Patients with Advanced c-MET-positive Non-Small Cell Lung Cancer Phase Ib (China only): Approximately 90 patients Phase Ⅱ (globally): Approximately 78 evaluable patients; addition of at least 6 patients in Safety Run-in (US only)
What is the current status of trial NCT04270591?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 183 participants. The study started on 2019-07-15. Estimated completion is 2023-12-30.
What conditions does trial NCT04270591 study?
This clinical trial studies the following conditions: C-Met Exon 14 Mutation. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04270591?
The interventions under investigation include: Glumetinib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04270591?
This trial is sponsored by Haihe Biopharma Co., which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04270591 being conducted?
This trial has 20 study locations across Kentucky, Anhui, Beijing Municipality, Fujian, Guangdong. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How Clinical Trials Work
Understand phases 1-4, trial design, randomization, and the informed consent process.
Patient Rights in Clinical Trials
Your rights as a participant: consent, withdrawal, privacy, and who to contact.
Finding the Right Clinical Trial
A practical guide to searching trials, understanding eligibility, and evaluating options.
All Guides
Browse our complete library of clinical trial educational resources.
Read our methodology — how this data is sourced, computed, and verified.