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Minds and Mentors Program- R33
NCT05363371 · View on ClinicalTrials.gov ↗
Study Summary
The proposed research effort will: The purpose of this study is as follows: 1. Test the effectiveness of the Minds and Mentors Program in a group treatment trial in which individuals using medications for opioid use disorder (MOUD) will be randomized in blocks of five to receive either the Minds and Mentors Program (n=120) or Twelve Step Facilitation (n=120). 2. Determine whether the MiMP: a) improves adherence to MOUD b) reduces the rate of relapse and cravings c) decreases self-reported anxiety, stress, and depression and d) reduces cortisol levels and cortisol reactivity to drug cues. 3. Examine whether pre-intervention cortisol reactivity is predictive of relapse outcomes, and/ or reductions in cortisol reactivity over the course of intervention mediate relapse outcomes.
Conditions Studied
Interventions
- BEHAVIORAL Minds and Mentors
- BEHAVIORAL Twelve Step Intervention Group
Study Locations (4)
Alabama
- Birmingham Veteran Affairs Medical Center — Birmingham
- Pathway Healthcare, LLC — Birmingham
- Tuscaloosa Veteran Affairs Medical Center — Tuscaloosa
- University of Alabama — Tuscaloosa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 240 participants |
| Start Date | 2022-01-04 |
| Est. Completion | 2024-08-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05363371
The ClinicalTrials.gov registry entry for NCT05363371 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 240 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Alabama, Tuscaloo, which has 76 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Opioid Use Disorder appearing as the primary indexed condition, and to 2 interventions — of which Minds and Mentors is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05363371 reports 4 study locations spanning 1 distinct geographic area — top geographies include Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05363371 about?
NCT05363371 is a clinical study titled "Minds and Mentors Program- R33". The proposed research effort will: The purpose of this study is as follows: 1. Test the effectiveness of the Minds and Mentors Program in a group treatment trial in which individuals using medications for opioid use disorder (MOUD) will be randomized in blocks of five to receive either the Minds a...
What is the current status of trial NCT05363371?
This trial is currently recruiting. It is a NA study. The enrollment target is 240 participants. The study started on 2022-01-04. Estimated completion is 2024-08-31.
What conditions does trial NCT05363371 study?
This clinical trial studies the following conditions: Opioid Use Disorder, Substance Use Disorders, Medication Assisted Treatment. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05363371?
The interventions under investigation include: Minds and Mentors (BEHAVIORAL), Twelve Step Intervention Group (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05363371?
This trial is sponsored by University of Alabama, Tuscaloo, which has 76 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05363371 being conducted?
This trial has 4 study locations across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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