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NCT05300724 · ClinicalTrials.gov registry record
An Observational Study of the Progression of Intermediate Age-Related Macular Degeneration
A clinical trial of Age-related Macular Degeneration, sponsored by Genentech.
- Active
- Registry status
- 400
- Enrollment target
- 20
- Study locations
NCT05300724: Active study of Age-related Macular Degeneration, sponsored by Genentech.
NCT05300724 is a study of Age-related Macular Degeneration that is active but no longer recruiting, run by Genentech. The registered enrollment target is 400 participants, below the 1,502-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (73% lower). The trial reports 20 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05300724, a study of Age-related Macular Degeneration, is active but no longer recruiting, sponsored by Genentech.
- ACTIVE NOT RECRUITING
- Registry status
- 400 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a multicenter prospective study in participants with intermediate age-related macular degeneration (iAMD). One primary objective of this study is to assess iAMD disease progression, by the timeline and rates of conversion for high-risk iAMD at baseline to more advanced atrophic AMD stages. The other primary objective of this observational study is to assess the feasibility of measuring the rate of photoreceptor loss as a potential clinical endpoint. The study will consist of an observation period of approximately 3 years (\~144 weeks) for participants.
Conditions Studied
Interventions
- OTHER No intervention
Study Locations (20)
California
- The Retina Partners - Encino
- Retina Consultants of Orange County - Fullerton
- Northern California Retina Vitreous Associates - Mountain View
- Retina Consultants, San Diego - Poway
- UC Davis Eye Center - Sacramento
- Retinal Consultants Medical Group - Sacramento
- Bay Area Retina Associates - Walnut Creek
Florida
- Advanced Research - Coral Springs
- Rand Eye Institute - Deerfield Beach
- National Ophthalmic Research Institute - Fort Myers
- Florida Eye Associates - Melbourne
Colorado
- Southwest Retina Consultants - Durango
- Eye Care Center of Northern Colorado PC - Longmont
Arkansas
- Retina Partners of Northwest Arkansas, PLLC - Springdale
Georgia
- Southeast Retina Center - Augusta
Illinois
- University Retina and Macula Associates, PC - Oak Forest
Indiana
- Raj K. Maturi, MD PC - Indianapolis
Iowa
- Wolfe Eye Clinic - West Des Moines
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2022-05-27 |
| Est. Completion | 2027-06-30 |
What the registry record for NCT05300724 still lists
NCT05300724 is an observational study that tracks outcomes without assigning an intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 1,502-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (73% lower).
The record links to 1 condition, with Age-related Macular Degeneration appearing as the primary indexed condition, and to 1 intervention - of which No intervention is the first listed.
NCT05300724 names 20 study sites across 10 states, led by California, Florida, Colorado.
Frequently Asked Questions
What is clinical trial NCT05300724 about?
NCT05300724 is a clinical study titled "An Observational Study of the Progression of Intermediate Age-Related Macular Degeneration". This is a multicenter prospective study in participants with intermediate age-related macular degeneration (iAMD). One primary objective of this study is to assess iAMD disease progression, by the timeline and rates of conversion for high-risk iAMD at baseline to more advanced atrophic AMD stages. T...
What is the current status of trial NCT05300724?
This trial is currently active not recruiting. The enrollment target is 400 participants. The study started on 2022-05-27. Estimated completion is 2027-06-30.
What conditions does trial NCT05300724 study?
This clinical trial studies the following conditions: Age-related Macular Degeneration.
What interventions are being tested in trial NCT05300724?
The interventions under investigation include: No intervention (OTHER).
Who is sponsoring clinical trial NCT05300724?
This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05300724 being conducted?
This trial has 20 study locations across Arkansas, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05300724's enrollment target sits among peer trials
400 13th of 74 higher than 62 of 74 other Age-related Macular Degeneration trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Age-related Macular Degeneration trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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