Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05278039 · ClinicalTrials.gov registry record · NA

Training Swallowing Initiation During Expiration

A NA study of Head and Neck Cancer and Dysphagia, sponsored by Northwestern University.

Recruiting
Registry status
NA
Development phase
88
Enrollment target
2
Study locations

NCT05278039: Recruiting NA study of Head and Neck Cancer and Dysphagia, sponsored by Northwestern University.

NCT05278039 is a NA study of Head and Neck Cancer and Dysphagia that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 88 participants, below the 260-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (66% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05278039, a NA study of Head and Neck Cancer and Dysphagia, is actively recruiting participants, sponsored by Northwestern University.

RECRUITING
Registry status
NA
Development phase
88 participants
Enrollment target
2
Study locations

Study Summary

Head and neck cancers have escalated to epidemic levels in the United States, and survivors are suffering from life-long, devastating swallowing disorders with limited therapeutic options. This clinical trial investigates a novel swallowing treatment that trains initiation of swallowing during the expiratory phase of respiration to improve swallowing safety and efficiency.

Primary Outcome

Determines percent (frequency) of the target (expiratory phase) for each swallow.

Interventions

  • BEHAVIORAL Respiratory-Swallow Phase Training
  • OTHER Swallow Practice

Study Locations (2)

Illinois

  • Northwestern Memorial Hospital - Chicago
  • Northwestern University - Evanston

Trial Details

FieldValue
Enrollment Target 88 participants
Start Date 2022-05-19
Est. Completion 2027-07-31
Phase NA
Northwestern University

1,209 total trials

What NCT05278039 shows while recruiting

NCT05278039 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 88 participants, a relatively small participant target, below the 260-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (66% lower).

The record links to 4 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 2 interventions - of which Respiratory-Swallow Phase Training is the first listed.

NCT05278039 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT05278039 about?

NCT05278039 is a clinical study titled "Training Swallowing Initiation During Expiration". Head and neck cancers have escalated to epidemic levels in the United States, and survivors are suffering from life-long, devastating swallowing disorders with limited therapeutic options. This clinical trial investigates a novel swallowing treatment that trains initiation of swallowing during the e...

What is the current status of trial NCT05278039?

This trial is currently recruiting. It is a NA study. The enrollment target is 88 participants. The study started on 2022-05-19. Estimated completion is 2027-07-31.

What conditions does trial NCT05278039 study?

This clinical trial studies the following conditions: Head and Neck Cancer, Dysphagia, Oropharyngeal Dysphagia, Oropharynx Squamous Cell Carcinoma.

What interventions are being tested in trial NCT05278039?

The interventions under investigation include: Respiratory-Swallow Phase Training (BEHAVIORAL), Swallow Practice (OTHER).

Who is sponsoring clinical trial NCT05278039?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05278039 being conducted?

This trial has 2 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Head and Neck Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05278039's enrollment target sits among peer trials

88 95th of 250 higher than 156 of 250 other Head and Neck Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Head and Neck Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03843463 · 88 participants · Phase 2

    Escitalopram and Language Intervention for Subacute Aphasia

  • NCT04066348 · 88 participants · Phase 2

    TNF-α Treatment of Blast-Induced Tinnitus

  • NCT04331704 · 88 participants · Phase 4

    ANCHORS Alcohol & Sexual Health Study: UH3 Project

  • NCT04536103 · 88 participants

    Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05278039, the US trial registry maintained by the National Library of Medicine. NCT05278039 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.