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RECRUITING NA

His-Bundle Corrective Pacing in Heart Failure

NCT05265520 · View on ClinicalTrials.gov ↗

Study Summary

The investigators aim to prospectively evaluate the efficacy and mechanism of benefit of His-bundle pacing enhanced cardiac resynchronization therapy (His-CRT) vs. cardiac resynchronization therapy (BIV-CRT) in patients with heart failure and right bundle branch block (RBBB).

Interventions

  • PROCEDURE His-CRT implantation
  • PROCEDURE BIV-CRT implantation

Study Locations (14)

Illinois

  • Northwestern Memorial Hospital — Chicago
  • Rush University Medical Center — Chicago
  • University of Chicago — Chicago

New York

  • Weill Cornell Medical College — New York
  • Mount Sinai Hospital — New York

Pennsylvania

  • University of Pennsylvania — Philadelphia
  • Geisinger Wyoming Valley — Wilkes-Barre

Arizona

  • University of Arizona — Phoenix

California

  • Cedars-Sinai Medical Center — Los Angeles

Florida

  • University of South Florida — Tampa

New Jersey

  • Valley Health System — Ridgewood

North Carolina

  • Mission Health — Asheville

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2022-12-02
Est. Completion 2028-07-01
Phase NA

Sponsor

University of Rochester

437 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05265520

The ClinicalTrials.gov registry entry for NCT05265520 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Rochester, which has 437 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Heart Failure appearing as the primary indexed condition, and to 2 interventions — of which His-CRT implantation is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05265520 reports 14 study locations spanning 10 distinct geographic areas — top geographies include Illinois, New York, Pennsylvania. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05265520 about?

NCT05265520 is a clinical study titled "His-Bundle Corrective Pacing in Heart Failure". The investigators aim to prospectively evaluate the efficacy and mechanism of benefit of His-bundle pacing enhanced cardiac resynchronization therapy (His-CRT) vs. cardiac resynchronization therapy (BIV-CRT) in patients with heart failure and right bundle branch block (RBBB).

What is the current status of trial NCT05265520?

This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2022-12-02. Estimated completion is 2028-07-01.

What conditions does trial NCT05265520 study?

This clinical trial studies the following conditions: Heart Failure, Cardiac Resynchronization Therapy, Right Bundle-Branch Block, His-bundle Pacing. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05265520?

The interventions under investigation include: His-CRT implantation (PROCEDURE), BIV-CRT implantation (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05265520?

This trial is sponsored by University of Rochester, which has 437 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05265520 being conducted?

This trial has 14 study locations across Arizona, California, Florida, Illinois, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial