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NCT05167721 · ClinicalTrials.gov registry record · Phase 2
Randomized Double-Blind Placebo-Controlled Adaptive Design Trial Of Intrathecally Administered Autologous Mesenchymal Stem Cells In Multiple System Atrophy
A Phase 2 study of Multiple System Atrophy, sponsored by Mayo Clinic.
- Active
- Registry status
- Phase 2
- Development phase
- 71
- Enrollment target
- 1
- Study location
NCT05167721 is a Phase 2 study of Multiple System Atrophy that is active but no longer recruiting, run by Mayo Clinic. The registered enrollment target is 71 participants, below the 266-participant average among 30 other Multiple System Atrophy trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05167721, a Phase 2 study of Multiple System Atrophy, is active but no longer recruiting, sponsored by Mayo Clinic.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 71 participants
- Enrollment target
- 1
- Study location
Study Summary
Multiple system atrophy (MSA) is a rare, rapidly progressive, and invariably fatal neurological condition characterized by autonomic failure, parkinsonism, and/or ataxia. There is no available treatment to slow or halt disease progression. The purpose of this study is to assess optimal dosing frequency, effectiveness and safety of adipose-derived autologous mesenchymal stem cells delivered into the spinal fluid of patients with MSA. Funding source: FDA Office of Orphan Product Development (OOPD), Mayo Clinic Executive Dean for Research Transformational Award, Mayo Clinic Regenerative Medicine, and Mayo Clinic Department of Neurology.
Conditions Studied
Interventions
- OTHER Placebo
- BIOLOGICAL Autologous Mesenchymal Stem Cells
Study Locations (1)
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 71 participants |
| Start Date | 2021-12-15 |
| Est. Completion | 2026-12 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05167721
The ClinicalTrials.gov registry entry for NCT05167721 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 71 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 266-participant average among 30 other Multiple System Atrophy trials with a reported enrollment target (73% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Multiple System Atrophy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05167721 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.
Frequently Asked Questions
What is clinical trial NCT05167721 about?
NCT05167721 is a clinical study titled "Randomized Double-Blind Placebo-Controlled Adaptive Design Trial Of Intrathecally Administered Autologous Mesenchymal Stem Cells In Multiple System Atrophy". Multiple system atrophy (MSA) is a rare, rapidly progressive, and invariably fatal neurological condition characterized by autonomic failure, parkinsonism, and/or ataxia. There is no available treatment to slow or halt disease progression. The purpose of this study is to assess optimal dosing freque...
What is the current status of trial NCT05167721?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 71 participants. The study started on 2021-12-15. Estimated completion is 2026-12.
What conditions does trial NCT05167721 study?
This clinical trial studies the following conditions: Multiple System Atrophy.
What interventions are being tested in trial NCT05167721?
The interventions under investigation include: Placebo (OTHER), Autologous Mesenchymal Stem Cells (BIOLOGICAL).
Who is sponsoring clinical trial NCT05167721?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05167721 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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