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NCT04620382 · ClinicalTrials.gov registry record · Early Phase 1
Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients
A Early Phase 1 study of Parkinson Disease and Multiple System Atrophy, sponsored by Vanderbilt University Medical Center.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 31
- Enrollment target
- 1
- Study location
NCT04620382 is a Early Phase 1 study of Parkinson Disease and Multiple System Atrophy that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 31 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04620382, a Early Phase 1 study of Parkinson Disease and Multiple System Atrophy, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 31 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to learn more about the effects of abdominal compression and the medication midodrine, two interventions used for the treatment of orthostatic hypotension (low blood pressure on standing), on hemodynamic markers of cardiovascular risk. The study will be conducted at the Vanderbilt University Medical Center and consists of a screening and 2 testing days, one with abdominal compression and one with midodrine. The total length of the study will be about 5 days.
Conditions Studied
Interventions
- DRUG Midodrine
- DRUG Placebo pill
- DEVICE Abdominal compression
- DEVICE sham compression
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2020-11-09 |
| Est. Completion | 2026-12-01 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04620382
The ClinicalTrials.gov registry entry for NCT04620382 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 31 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Parkinson Disease appearing as the primary indexed condition, and to 4 interventions - of which Midodrine is the first listed.
NCT04620382 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT04620382 about?
NCT04620382 is a clinical study titled "Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients". The purpose of this study is to learn more about the effects of abdominal compression and the medication midodrine, two interventions used for the treatment of orthostatic hypotension (low blood pressure on standing), on hemodynamic markers of cardiovascular risk. The study will be conducted at the ...
What is the current status of trial NCT04620382?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 31 participants. The study started on 2020-11-09. Estimated completion is 2026-12-01.
What conditions does trial NCT04620382 study?
This clinical trial studies the following conditions: Parkinson Disease, Multiple System Atrophy, Autonomic Failure, Pure Autonomic Failure, Neurogenic Orthostatic Hypotension.
What interventions are being tested in trial NCT04620382?
The interventions under investigation include: Midodrine (DRUG), Placebo pill (DRUG), Abdominal compression (DEVICE), sham compression (DEVICE).
Who is sponsoring clinical trial NCT04620382?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04620382 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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