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NCT05159440 · ClinicalTrials.gov registry record · Phase 1

First in Human Study of TORL-2-307-MAB in Participants With Advanced Cancer

A Phase 1 study of Advanced Solid Tumor and Gastric Cancer, sponsored by TORL Biotherapeutics.

Active
Registry status
Phase 1
Development phase
70
Enrollment target
8
Study locations

NCT05159440 is a Phase 1 study of Advanced Solid Tumor and Gastric Cancer that is active but no longer recruiting, run by TORL Biotherapeutics. The registered enrollment target is 70 participants, below the 193-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target (64% lower). The trial reports 8 study locations across 4 states.

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The verdict

NCT05159440, a Phase 1 study of Advanced Solid Tumor and Gastric Cancer, is active but no longer recruiting, sponsored by TORL Biotherapeutics.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
70 participants
Enrollment target
8
Study locations

Study Summary

This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-2-307-MAB in patients with advanced cancer

Conditions Studied

Advanced Solid Tumor Gastric Cancer Pancreas Cancer Gastroesophageal Junction Adenocarcinoma

Interventions

  • DRUG TORL-2-307-MAB

Study Locations (8)

California

  • Providence St. Jude Medical Center - Fullerton
  • UCLA - JCCC Clinical Research Unit - Los Angeles
  • Torrance Memorial Medical - Torrance

Other

  • Seoul National University Hospital - Seoul
  • Severance Hospital, Yonsei University Health System - Seoul
  • Seoul National University Bundang Hospital - Seoul

Indiana

  • Fort Wayne Medical Oncology and Hematology - Fort Wayne

Missouri

  • Washington University School of Medicine-Siteman Cancer Center - St Louis

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2022-01-20
Est. Completion 2025-12-15
Phase Phase 1

Sponsor

TORL Biotherapeutics

8 total trials

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What the Registry Record Tells You About NCT05159440

The ClinicalTrials.gov registry entry for NCT05159440 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 193-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target (64% lower). The listed sponsor is TORL Biotherapeutics, which has 8 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Advanced Solid Tumor appearing as the primary indexed condition, and to 1 intervention - of which TORL-2-307-MAB is the first listed.

NCT05159440 reports 8 study locations spanning 4 distinct geographic areas - top geographies include California, Other, Indiana.

Frequently Asked Questions

What is clinical trial NCT05159440 about?

NCT05159440 is a clinical study titled "First in Human Study of TORL-2-307-MAB in Participants With Advanced Cancer". This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-2-307-MAB in patients with advanced cancer

What is the current status of trial NCT05159440?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 70 participants. The study started on 2022-01-20. Estimated completion is 2025-12-15.

What conditions does trial NCT05159440 study?

This clinical trial studies the following conditions: Advanced Solid Tumor, Gastric Cancer, Pancreas Cancer, Gastroesophageal Junction Adenocarcinoma.

What interventions are being tested in trial NCT05159440?

The interventions under investigation include: TORL-2-307-MAB (DRUG).

Who is sponsoring clinical trial NCT05159440?

This trial is sponsored by TORL Biotherapeutics, which has 8 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05159440 being conducted?

This trial has 8 study locations across California, Indiana, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.