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NCT05585775 · ClinicalTrials.gov registry record · NA
Mood and Thought Process Study
A NA study of Depression and Depressive Symptoms, sponsored by Butler Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 76
- Enrollment target
- 1
- Study location
NCT05585775: Recruiting NA study of Depression and Depressive Symptoms, sponsored by Butler Hospital.
NCT05585775 is a NA study of Depression and Depressive Symptoms that is actively recruiting participants, run by Butler Hospital. The registered enrollment target is 76 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05585775, a NA study of Depression and Depressive Symptoms, is actively recruiting participants, sponsored by Butler Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 76 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary objective for this project is to test whether affective executive functioning is a mechanism of action of mindfulness-based cognitive therapy and Wellness for Wellbeing. The main questions it aims to answer are: 1. Test the effect of MBCT vs. Wellness for Wellbeing on affective inhibition (i.e., emotionally valenced inhibition as measured via the affective Go/No Go task) using an RCT. 2. Test the effect of MBCT vs. Wellness for Wellbeing on (a) affective updating and (b) affective shifting. Outcomes will be measured with the affective n-Back and the affective Internal Switching Task, respectively. 3a) The investigators will examine whether depression symptom severity co-varies with change in affective executive functioning (i.e., affecting inhibition, shifting, and updating) over time. 3b) The investigators will examine whether compliance with treatment protocol (e.g., number of classes attended, amount of home practice) predicts endpoint executive functioning. Participants will complete surveys, interviews, and computer tasks, and will be randomized to either Mindfulness-Based Cognitive Therapy or Wellness for Wellbeing.
Primary Outcome
This task requires utilizing inhibition to respond to word features (i.e., normal vs. italicized font) rather than word content. In this task, participants are told to respond (via key press) when a go stimulus (i.e., normal text) is presented and to withhold their response when a no-go stimulus (i.e., italicized text) is presented. words are negatively valenced (e.g., hate, sad) or positively valenced (e.g., terrific, win). Conditions are matched on word length and frequency of use in the Engli
Conditions Studied
Interventions
- BEHAVIORAL Mindfulness-Based Cognitive Therapy
- BEHAVIORAL Wellness for Wellbeing
Study Locations (1)
Rhode Island
- Butler Hospital - Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 76 participants |
| Start Date | 2023-04-06 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT05585775 shows while recruiting
NCT05585775 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (90% lower).
The record links to 3 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Mindfulness-Based Cognitive Therapy is the first listed.
NCT05585775 reports a single indexed study location in Rhode Island.
Frequently Asked Questions
What is clinical trial NCT05585775 about?
NCT05585775 is a clinical study titled "Mood and Thought Process Study". The primary objective for this project is to test whether affective executive functioning is a mechanism of action of mindfulness-based cognitive therapy and Wellness for Wellbeing. The main questions it aims to answer are: 1. Test the effect of MBCT vs. Wellness for Wellbeing on affective inhibiti...
What is the current status of trial NCT05585775?
This trial is currently recruiting. It is a NA study. The enrollment target is 76 participants. The study started on 2023-04-06. Estimated completion is 2026-12-31.
What conditions does trial NCT05585775 study?
This clinical trial studies the following conditions: Depression, Depressive Symptoms, Depression in Remission.
What interventions are being tested in trial NCT05585775?
The interventions under investigation include: Mindfulness-Based Cognitive Therapy (BEHAVIORAL), Wellness for Wellbeing (BEHAVIORAL).
Who is sponsoring clinical trial NCT05585775?
This trial is sponsored by Butler Hospital, which has 103 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05585775 being conducted?
This trial has 1 study location across Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05585775's enrollment target sits among peer trials
76 384th of 679 higher than 294 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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