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Supporting Treatment Access and Recovery in COD
NCT05138614 · View on ClinicalTrials.gov ↗
Study Summary
This 4-year study will randomize 1,000 people with co-occurring opioid use and mental health disorders (COD) at medication for opioid use disorder (MOUD) clinics to evaluate the effectiveness of MISSION, a multi-component team approach, or its components with MOUD versus MOUD alone, as well as the incremental benefits of MISSION or its components for improving outcomes. We expect that individuals receiving MISSION or its parts + MOUD will show greater improvement over MOUD alone on: engagement, substance use, and mental health.
Conditions Studied
Interventions
- OTHER Medication for Opioid Use Disorder
- BEHAVIORAL MISSION Critical Time Intervention
- BEHAVIORAL MISSION Peer Support
- BEHAVIORAL MISSION Dual Recovery Therapy
Study Locations (5)
Massachusetts
- Behavioral Health Network — Holyoke
- Behavioral Health Network — Orange
- Behavioral Health Network — Springfield
- UMass Chan Road to Care Clinic — Worcester
- SaVida Health — Worcester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2022-03-11 |
| Est. Completion | 2026-08-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05138614
The ClinicalTrials.gov registry entry for NCT05138614 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Massachusetts, Worcester, which has 200 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Opioid Use Disorder appearing as the primary indexed condition, and to 4 interventions — of which Medication for Opioid Use Disorder is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05138614 reports 5 study locations spanning 1 distinct geographic area — top geographies include Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05138614 about?
NCT05138614 is a clinical study titled "Supporting Treatment Access and Recovery in COD". This 4-year study will randomize 1,000 people with co-occurring opioid use and mental health disorders (COD) at medication for opioid use disorder (MOUD) clinics to evaluate the effectiveness of MISSION, a multi-component team approach, or its components with MOUD versus MOUD alone, as well as the i...
What is the current status of trial NCT05138614?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,000 participants. The study started on 2022-03-11. Estimated completion is 2026-08-31.
What conditions does trial NCT05138614 study?
This clinical trial studies the following conditions: Opioid Use Disorder, Mental Health Disorder. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05138614?
The interventions under investigation include: Medication for Opioid Use Disorder (OTHER), MISSION Critical Time Intervention (BEHAVIORAL), MISSION Peer Support (BEHAVIORAL), MISSION Dual Recovery Therapy (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05138614?
This trial is sponsored by University of Massachusetts, Worcester, which has 200 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05138614 being conducted?
This trial has 5 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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