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NCT05112432 · ClinicalTrials.gov registry record · NA
EPI-MINN: Targeting Cognition and Motivation
A NA study of Psychosis, sponsored by University of Minnesota.
- Active
- Registry status
- NA
- Development phase
- 400
- Enrollment target
- 3
- Study locations
NCT05112432: Active NA study of Psychosis, sponsored by University of Minnesota.
NCT05112432 is a NA study of Psychosis that is active but no longer recruiting, run by University of Minnesota. The registered enrollment target is 400 participants, above the 167-participant average among 35 other Psychosis trials with a reported enrollment target (140% higher). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05112432, a NA study of Psychosis, is active but no longer recruiting, sponsored by University of Minnesota.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 400 participants
- Enrollment target
- 3
- Study locations
Study Summary
The purpose of this study is to perform a practice-based research project designed to assess whether cognition and motivated behavior in early psychosis can be addressed as key treatment goals within real-world settings by using a 12-week mobile intervention program. Participants who are enrolled in a chart review study of measurement-based care will be recruited to participate in this study. In the measurement-based care study, participants are enrolled in coordinated specialty care programs for early psychosis that provide comprehensive clinical services such as psychotherapy, medication management, psychoeducation, work or education support, and measurement-based care. Participants will complete a set of well-defined measures every 6 months that assess symptoms, functioning, cognition and motivation as standard of care. The current study will utilize the data acquired in the measurement-based care study. The aim of this study is to investigate a well-defined 12-week mobile intervention program specifically designed to target cognitive functioning and motivated behavior for individuals with early psychosis. The investigators will test for differences in the clinical trajectories over 18 months in those who receive the intervention vs. those who do not. This study will be conducted jointly with a sister protocol under a separate NCT listing. This iteration will be conducted locally within the EPI-MINN Network, while the other project will be conducted on a national scale.
Primary Outcome
Penn CNP is reported as the total score on 4 cognitive domains. The DSST ranges from 0-300+, the PWMT ranges from 0-40, the PMAT ranges from 0-24, and the ER-40 ranges from 0-40. Penn CNP will be assessed at baseline, during pre-training, at 6 months, 12 months, and 18 months. Higher accuracy scores indicate higher cognitive function and lower reaction time scores indicate faster reaction time. Reaction time is reported in milliseconds. Performance score is calculated based on accuracy and react
Conditions Studied
Interventions
- DEVICE Cognitive and Social Cognitive Training
- BEHAVIORAL Personalized Real-Time Intervention for Motivational Enhancement (PRIME) App
- OTHER Early Psychosis Coordinated Specialty Care
Study Locations (3)
Minnesota
- Human Development Center - Duluth
- Hennepin Healthcare - Minneapolis
- University of Minnesota - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2021-08-12 |
| Est. Completion | 2026-07-31 |
| Phase | NA |
What the registry record for NCT05112432 still lists
NCT05112432 is an interventional study that assigns participants to a tested intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, above the 167-participant average among 35 other Psychosis trials with a reported enrollment target (140% higher).
The record links to 1 condition, with Psychosis appearing as the primary indexed condition, and to 3 interventions - of which Cognitive and Social Cognitive Training is the first listed.
NCT05112432 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT05112432 about?
NCT05112432 is a clinical study titled "EPI-MINN: Targeting Cognition and Motivation". The purpose of this study is to perform a practice-based research project designed to assess whether cognition and motivated behavior in early psychosis can be addressed as key treatment goals within real-world settings by using a 12-week mobile intervention program. Participants who are enrolled in...
What is the current status of trial NCT05112432?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 400 participants. The study started on 2021-08-12. Estimated completion is 2026-07-31.
What conditions does trial NCT05112432 study?
This clinical trial studies the following conditions: Psychosis.
What interventions are being tested in trial NCT05112432?
The interventions under investigation include: Cognitive and Social Cognitive Training (DEVICE), Personalized Real-Time Intervention for Motivational Enhancement (PRIME) App (BEHAVIORAL), Early Psychosis Coordinated Specialty Care (OTHER).
Who is sponsoring clinical trial NCT05112432?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05112432 being conducted?
This trial has 3 study locations across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05112432's enrollment target sits among peer trials
400 2nd of 35 the highest of 35 other Psychosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Psychosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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