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NCT05067179 · ClinicalTrials.gov registry record
Analysis of Human ALS Tissues and Registry of ALS Patients
A clinical trial of Amyotrophic Lateral Sclerosis, sponsored by University of Illinois at Chicago.
- Recruiting
- Registry status
- 40
- Enrollment target
- 1
- Study location
NCT05067179: Recruiting study of Amyotrophic Lateral Sclerosis, sponsored by University of Illinois at Chicago.
NCT05067179 is a study of Amyotrophic Lateral Sclerosis that is actively recruiting participants, run by University of Illinois at Chicago. The registered enrollment target is 40 participants, below the 898-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05067179, a study of Amyotrophic Lateral Sclerosis, is actively recruiting participants, sponsored by University of Illinois at Chicago.
- RECRUITING
- Registry status
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Amyotrophic Lateral Sclerosis (ALS), often referred to as Lou Gehrig's Disease, is a progressive, terminal condition of muscle weakness that is associated with degeneration of neurons in the spinal cord and brain. This devastating disorder afflicts people in the prime of their lives. At the present time, there are no cures for this disorder, and current treatments are marginal at best. Despite years of intensive research, a fundamental understanding of this disease is still lacking. There is a need to identify both reliable markers of disease progression and effective treatments. The goal of this research is to bring a greater understanding of ALS patients closer to the research studies that can lead to new hypotheses and approaches.
Primary Outcome
High resolution 3T MRI T1, T2/FLAIR, DWI, SWI, MRS, and MT sequences at the cervical, thoracic, and lumbar spine and brainstem will be used to identify individual and combinatorial (of each sequence) changes to be used as clinical biomarkers of progression in cases with focal disease onset and spread. These will be compared to histologic and genomic changes in rapid postmortem tissues in the same areas. High resolution T1-weighted imaging is preferred for anatomical structure morphometry. The hy
Conditions Studied
Study Locations (1)
Illinois
- University of Illinois at Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2020-09-01 |
| Est. Completion | 2030-01-01 |
What NCT05067179 shows while recruiting
NCT05067179 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 898-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Amyotrophic Lateral Sclerosis appearing as the primary indexed condition, and to 0 interventions.
NCT05067179 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT05067179 about?
NCT05067179 is a clinical study titled "Analysis of Human ALS Tissues and Registry of ALS Patients". Amyotrophic Lateral Sclerosis (ALS), often referred to as Lou Gehrig's Disease, is a progressive, terminal condition of muscle weakness that is associated with degeneration of neurons in the spinal cord and brain. This devastating disorder afflicts people in the prime of their lives. At the present ...
What is the current status of trial NCT05067179?
This trial is currently recruiting. The enrollment target is 40 participants. The study started on 2020-09-01. Estimated completion is 2030-01-01.
What conditions does trial NCT05067179 study?
This clinical trial studies the following conditions: Amyotrophic Lateral Sclerosis.
Who is sponsoring clinical trial NCT05067179?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05067179 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05067179's enrollment target sits among peer trials
40 58th of 102 higher than 44 of 102 other Amyotrophic Lateral Sclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Amyotrophic Lateral Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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