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Groningen International Study on Sentinel Nodes in Vulvar Cancer-III
NCT05076942 · View on ClinicalTrials.gov ↗
Study Summary
Vulvar cancer patients with SN-metastasis \> 2mm will receive chemoradiation instead of an inguinofemoral lymphadenectomy.
Conditions Studied
Interventions
- DRUG Cisplatin
- RADIATION Radiotherapy combined with cisplatin
Study Locations (20)
New York
- Memorial Sloan Kettering Commack — Commack
- Memorial Sloan Kettering Westchester — Harrison
- Memorial Sloan Kettering Cancer Center — New York
- Memorial Sloan Kettering Nassau — Uniondale
New Jersey
- Memorial Sloan Kettering Basking Ridge — Basking Ridge
- Memorial Sloan Kettering Monmouth — Middletown
- Memorial Sloan Kettering Bergen — Montvale
Michigan
- Spectrum Health at Butterworth Campus — Grand Rapids
- Munson Medical Center — Traverse City
North Carolina
- Duke University Medical Center — Durham
- Duke Women's Cancer Care Raleigh — Raleigh
Ohio
- Ohio State University Comprehensive Cancer Center — Columbus
- ProMedica Flower Hospital — Sylvania
California
- UC Irvine Health/Chao Family Comprehensive Cancer Center — Orange
Florida
- Mount Sinai Medical Center — Miami Beach
Massachusetts
- Baystate Medical Center — Springfield
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 157 participants |
| Start Date | 2021-01-01 |
| Est. Completion | 2029-01-01 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05076942
The ClinicalTrials.gov registry entry for NCT05076942 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 157 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University Medical Center Groningen, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Vulvar Cancer appearing as the primary indexed condition, and to 2 interventions — of which Cisplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05076942 reports 20 study locations spanning 12 distinct geographic areas — top geographies include New York, New Jersey, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05076942 about?
NCT05076942 is a clinical study titled "Groningen International Study on Sentinel Nodes in Vulvar Cancer-III". Vulvar cancer patients with SN-metastasis \> 2mm will receive chemoradiation instead of an inguinofemoral lymphadenectomy.
What is the current status of trial NCT05076942?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 157 participants. The study started on 2021-01-01. Estimated completion is 2029-01-01.
What conditions does trial NCT05076942 study?
This clinical trial studies the following conditions: Vulvar Cancer, Sentinel Lymph Node, Lymph Node Metastases. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05076942?
The interventions under investigation include: Cisplatin (DRUG), Radiotherapy combined with cisplatin (RADIATION). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05076942?
This trial is sponsored by University Medical Center Groningen, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05076942 being conducted?
This trial has 20 study locations across California, Florida, Massachusetts, Michigan, Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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