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NCT05051618 · ClinicalTrials.gov registry record · NA
Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis
A NA study of Multiple Sclerosis and Major Depressive Disorder, sponsored by University of Illinois at Chicago.
- Recruiting
- Registry status
- NA
- Development phase
- 146
- Enrollment target
- 1
- Study location
NCT05051618: Recruiting NA study of Multiple Sclerosis and Major Depressive Disorder, sponsored by University of Illinois at Chicago.
NCT05051618 is a NA study of Multiple Sclerosis and Major Depressive Disorder that is actively recruiting participants, run by University of Illinois at Chicago. The registered enrollment target is 146 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05051618, a NA study of Multiple Sclerosis and Major Depressive Disorder, is actively recruiting participants, sponsored by University of Illinois at Chicago.
- RECRUITING
- Registry status
- NA
- Development phase
- 146 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research is to examine the effects of two different exercise training regimens for managing depression and improving other health indicators among persons with multiple sclerosis (MS). The project will enroll persons with MS and major depressive disorder (MDD) between 18 and 64 years of age. The investigators will enroll a total of 146 participants. This is a Phase-II trial that compares the efficacy of an exercise training program (POWER-MS) compared with a stretching program (FLEX-MS) for immediate and sustained reductions in the severity of depression among persons with MS who have MDD.
Primary Outcome
Patient Health Questionnaire (PHQ-9); scores range between 0 (min) and 27 (max), higher scores indicate greater depression severity.
Conditions Studied
Interventions
- BEHAVIORAL POWER-MS
- BEHAVIORAL FLEX-MS
Study Locations (1)
Illinois
- University of Illinois at Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 146 participants |
| Start Date | 2023-04-01 |
| Est. Completion | 2026-03-31 |
| Phase | NA |
What NCT05051618 shows while recruiting
NCT05051618 is an interventional study that assigns participants to a tested intervention. The registered 146 participants enrollment target is mid-sized for trials with a published cap, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (75% lower).
The record links to 2 conditions, with Multiple Sclerosis appearing as the primary indexed condition, and to 2 interventions - of which POWER-MS is the first listed.
NCT05051618 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT05051618 about?
NCT05051618 is a clinical study titled "Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis". The purpose of this research is to examine the effects of two different exercise training regimens for managing depression and improving other health indicators among persons with multiple sclerosis (MS). The project will enroll persons with MS and major depressive disorder (MDD) between 18 and 64 y...
What is the current status of trial NCT05051618?
This trial is currently recruiting. It is a NA study. The enrollment target is 146 participants. The study started on 2023-04-01. Estimated completion is 2026-03-31.
What conditions does trial NCT05051618 study?
This clinical trial studies the following conditions: Multiple Sclerosis, Major Depressive Disorder.
What interventions are being tested in trial NCT05051618?
The interventions under investigation include: POWER-MS (BEHAVIORAL), FLEX-MS (BEHAVIORAL).
Who is sponsoring clinical trial NCT05051618?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05051618 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05051618's enrollment target sits among peer trials
146 99th of 315 higher than 217 of 315 other Multiple Sclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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