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NCT05023434 · ClinicalTrials.gov registry record
A Study to Measure the Effect of Brain Stimulation on Hand Strength and Function in Patients With Brain Tumors
A clinical trial of Brain Tumor and Brain Cancer, sponsored by Medical College of Wisconsin.
- Active
- Registry status
- 60
- Enrollment target
- 1
- Study location
NCT05023434: Active study of Brain Tumor and Brain Cancer, sponsored by Medical College of Wisconsin.
NCT05023434 is a study of Brain Tumor and Brain Cancer that is active but no longer recruiting, run by Medical College of Wisconsin. The registered enrollment target is 60 participants, below the 281-participant average among 69 other Brain Tumor trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05023434, a study of Brain Tumor and Brain Cancer, is active but no longer recruiting, sponsored by Medical College of Wisconsin.
- ACTIVE NOT RECRUITING
- Registry status
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The neurosurgical standard of care for treating a patient with a tumor invading hand primary motor cortex (M1) includes performing a craniotomy with intraoperative direct electrical stimulation (DES) mapping and to resect as much tumor as possible without a resultant permanent neurological deficit. However, the subjective nature of current intraoperative hand motor assessments do not offer a comprehensive understanding of how hand strength and function may be impacted by resection. Additionally, there is a paucity of data to inform how altering DES parameters may effect motor mapping. Here, the investigators seek to demonstrate a feasible, standardized protocol to quantitatively assess hand strength and function and systematically assess several stimulation parameters to improve intraoperative measurements and better understand how cortical stimulation interacts with underlying neural function.
Primary Outcome
The categorization of stimulation frequencies (10, 30, 60, 130, and 250 Hz) as either inhibitory, facilitatory, or neutral, based on their impact on the finger individualization score.
Conditions Studied
Interventions
- PROCEDURE Intraoperative Brain Simulation - Alternate Stimulation Parameters
Study Locations (1)
Wisconsin
- Medical College of Wisconsin - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-09-08 |
| Est. Completion | 2026-10-01 |
What the registry record for NCT05023434 still lists
NCT05023434 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 281-participant average among 69 other Brain Tumor trials with a reported enrollment target (79% lower).
The record links to 3 conditions, with Brain Tumor appearing as the primary indexed condition, and to 1 intervention - of which Intraoperative Brain Simulation - Alternate Stimulation Parameters is the first listed.
NCT05023434 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT05023434 about?
NCT05023434 is a clinical study titled "A Study to Measure the Effect of Brain Stimulation on Hand Strength and Function in Patients With Brain Tumors". The neurosurgical standard of care for treating a patient with a tumor invading hand primary motor cortex (M1) includes performing a craniotomy with intraoperative direct electrical stimulation (DES) mapping and to resect as much tumor as possible without a resultant permanent neurological deficit. ...
What is the current status of trial NCT05023434?
This trial is currently active not recruiting. The enrollment target is 60 participants. The study started on 2021-09-08. Estimated completion is 2026-10-01.
What conditions does trial NCT05023434 study?
This clinical trial studies the following conditions: Brain Tumor, Brain Cancer, Motor Cortex; Lesion.
What interventions are being tested in trial NCT05023434?
The interventions under investigation include: Intraoperative Brain Simulation - Alternate Stimulation Parameters (PROCEDURE).
Who is sponsoring clinical trial NCT05023434?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05023434 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Brain Tumor
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05023434's enrollment target sits among peer trials
60 28th of 69 higher than 40 of 69 other Brain Tumor trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Brain Tumor trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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