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ACTIVE NOT RECRUITING Phase 2

Study of Zirconium Zr 89 Crefmirlimab Berdoxam PET/CT in Subjects With Advanced or Metastatic Malignancies

NCT05013099 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate whether zirconium Zr 89 crefmirlimab berdoxam (other names 89Zr-crefmirlimab berdoxam, 89Zr-Df-crefmirlimab, 89Zr-Df-IAB22M2C) PET/CT can predict the response of advanced or metastatic melanoma, Merkel cell carcinoma, renal cell carcinoma, or non-small cell lung cancer tumors to immuno-oncology therapy.

Interventions

  • BIOLOGICAL zirconium Zr 89 crefmirlimab berdoxam

Study Locations (16)

Other

  • University Hospitals Leuven — Leuven
  • Leiden University Medical Center — Leiden
  • Lausanne University Hospital — Lausanne
  • Northern Centre for Cancer Care and Newcastle University — Newcastle upon Tyne

California

  • City of Hope — Duarte
  • Providence Saint John's Cancer Institute — Santa Monica

Victoria

  • Olivia Newton-John Cancer Research Insititute — Heidelberg
  • Peter MacCallum Cancer Centre — Melbourne

Arkansas

  • CARTI Cancer Center — Little Rock

New York

  • Memorial Sloan Kettering Cancer Center — New York

Texas

  • UT Southwestern Medical Center — Dallas

Washington

  • University of Washington — Seattle

New South Wales

  • Macquarie University Hospital — Macquarie Park

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2021-12-09
Est. Completion 2025-07
Phase Phase 2

Sponsor

ImaginAb

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05013099

The ClinicalTrials.gov registry entry for NCT05013099 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is ImaginAb, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Melanoma appearing as the primary indexed condition, and to 1 intervention — of which zirconium Zr 89 crefmirlimab berdoxam is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05013099 reports 16 study locations spanning 11 distinct geographic areas — top geographies include Other, California, Victoria. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05013099 about?

NCT05013099 is a clinical study titled "Study of Zirconium Zr 89 Crefmirlimab Berdoxam PET/CT in Subjects With Advanced or Metastatic Malignancies". The purpose of this study is to evaluate whether zirconium Zr 89 crefmirlimab berdoxam (other names 89Zr-crefmirlimab berdoxam, 89Zr-Df-crefmirlimab, 89Zr-Df-IAB22M2C) PET/CT can predict the response of advanced or metastatic melanoma, Merkel cell carcinoma, renal cell carcinoma, or non-small cell l...

What is the current status of trial NCT05013099?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 70 participants. The study started on 2021-12-09. Estimated completion is 2025-07.

What conditions does trial NCT05013099 study?

This clinical trial studies the following conditions: Melanoma, Non Small Cell Lung Cancer, Renal Cell Carcinoma, Merkel Cell Carcinoma, Unspecified. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05013099?

The interventions under investigation include: zirconium Zr 89 crefmirlimab berdoxam (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05013099?

This trial is sponsored by ImaginAb, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05013099 being conducted?

This trial has 16 study locations across Arkansas, California, New York, Texas, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial