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NCT04989699 · ClinicalTrials.gov registry record · Phase 1
Study Evaluating the Treatment of OTX-TKI for Subjects With Neovascular Age-related Macular Degeneration
A Phase 1 study of Neovascular Age-related Macular Degeneration, sponsored by Ocular Therapeutix.
- Completed
- Registry status
- Phase 1
- Development phase
- 21
- Enrollment target
- 6
- Study locations
NCT04989699: Completed Phase 1 study of Neovascular Age-related Macular Degeneration, sponsored by Ocular Therapeutix.
NCT04989699 is a Phase 1 study of Neovascular Age-related Macular Degeneration that has completed, run by Ocular Therapeutix. The registered enrollment target is 21 participants, below the 408-participant average among 33 other Neovascular Age-related Macular Degeneration trials with a reported enrollment target (95% lower). The trial reports 6 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04989699, a Phase 1 study of Neovascular Age-related Macular Degeneration, has completed, sponsored by Ocular Therapeutix.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 21 participants
- Enrollment target
- 6
- Study locations
Study Summary
Evaluate the safety, tolerability, and efficacy of OTX-TKI for intravitreal use in subjects with Neovascular Age-Related Macular Degeneration
Primary Outcome
Incidence and severity of treatment emergent adverse events
Conditions Studied
Interventions
- DRUG OTX-TKI/Sham
- DRUG Aflibercept/Sham
Study Locations (6)
California
- Ocular Therapeutix - Bakersfield
- Ocular Therapeutix - Oxnard
Florida
- Ocular Therapeutix - Altamonte Springs
- Ocular Therapeutix - St. Petersburg
Nevada
- Ocular Therapeutix - Reno
Texas
- Ocular Therapeutix - The Woodlands
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2021-07-28 |
| Est. Completion | 2023-12-18 |
| Phase | Phase 1 |
What the finished NCT04989699 record still lists
NCT04989699 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 408-participant average among 33 other Neovascular Age-related Macular Degeneration trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Neovascular Age-related Macular Degeneration appearing as the primary indexed condition, and to 2 interventions - of which OTX-TKI/Sham is the first listed.
NCT04989699 lists 6 locations in 4 states (California, Florida, Nevada).
Frequently Asked Questions
What is clinical trial NCT04989699 about?
NCT04989699 is a clinical study titled "Study Evaluating the Treatment of OTX-TKI for Subjects With Neovascular Age-related Macular Degeneration". Evaluate the safety, tolerability, and efficacy of OTX-TKI for intravitreal use in subjects with Neovascular Age-Related Macular Degeneration
What is the current status of trial NCT04989699?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2021-07-28. Estimated completion is 2023-12-18.
What conditions does trial NCT04989699 study?
This clinical trial studies the following conditions: Neovascular Age-related Macular Degeneration.
What interventions are being tested in trial NCT04989699?
The interventions under investigation include: OTX-TKI/Sham (DRUG), Aflibercept/Sham (DRUG).
Who is sponsoring clinical trial NCT04989699?
This trial is sponsored by Ocular Therapeutix, which has 20 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04989699 being conducted?
This trial has 6 study locations across California, Florida, Nevada, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Neovascular Age-related Macular Degeneration
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04989699's enrollment target sits among peer trials
21 28th of 33 higher than 4 of 33 other Neovascular Age-related Macular Degeneration trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Neovascular Age-related Macular Degeneration trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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