Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04961047 · ClinicalTrials.gov registry record · NA

Feasibility and Efficacy of a Digital Neurotherapy Protocol for Management of Depression, Cognition, and Quality of Life in Cancer Survivors

A NA study, sponsored by Yale University.

Completed
Registry status
NA
Development phase
36
Enrollment target

NCT04961047: Completed NA study, sponsored by Yale University.

NCT04961047 is a NA study that has completed, run by Yale University. The registered enrollment target is 36 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04961047, a NA study, has completed, sponsored by Yale University.

COMPLETED
Registry status
NA
Development phase
36 participants
Enrollment target

Study Summary

This is a prospective, randomized clinical study to evaluate the feasibility and efficacy of a digital neurotherapy on depression, cognition, and quality of life in two groups of patients with major medical illness: 1) a sample of cancer survivors, and 2) a sample of patients with end stage kidney disease (ESKD) on dialysis.

Primary Outcome

Hospital Anxiety and Depression Questionnaire (HADS): This survey consists of 14 questions. The questions are related to the frequency of symptoms of anxiety and depression over the last week. Items are rated on a 0-3 scale, with several reverse-scored items. Scores range from 0 to 21. Higher scores indicate more severe symptoms. Administration time is 5 minutes.

Interventions

  • BEHAVIORAL Wait list control group
  • BEHAVIORAL Digital neurotherapy (DNT) Treatment

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2021-12-17
Est. Completion 2025-05-31
Phase NA
Yale University

1,492 total trials

What the finished NCT04961047 record still lists

NCT04961047 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 2 interventions - of which Wait list control group is the first listed.

NCT04961047 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04961047 about?

NCT04961047 is a clinical study titled "Feasibility and Efficacy of a Digital Neurotherapy Protocol for Management of Depression, Cognition, and Quality of Life in Cancer Survivors". This is a prospective, randomized clinical study to evaluate the feasibility and efficacy of a digital neurotherapy on depression, cognition, and quality of life in two groups of patients with major medical illness: 1) a sample of cancer survivors, and 2) a sample of patients with end stage kidney d...

What is the current status of trial NCT04961047?

This trial is currently completed. It is a NA study. The enrollment target is 36 participants. The study started on 2021-12-17. Estimated completion is 2025-05-31.

What interventions are being tested in trial NCT04961047?

The interventions under investigation include: Wait list control group (BEHAVIORAL), Digital neurotherapy (DNT) Treatment (BEHAVIORAL).

Who is sponsoring clinical trial NCT04961047?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04961047's enrollment target sits among peer trials

36 1541st of 2000 higher than 437 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00929006 · 36 participants · Early Phase 1

    Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism

  • NCT01891318 · 36 participants · Phase 1

    Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

  • NCT02291848 · 36 participants · Phase 1

    Tumor-Associated Antigen-Specific Cytotoxic T-Lymphocytes for Multiple Myeloma

  • NCT02366819 · 36 participants · Phase 4

    Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04961047, the US trial registry maintained by the National Library of Medicine. NCT04961047 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.