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NCT04874233 · ClinicalTrials.gov registry record · Phase 2

Phase 2a Study of HU6 in Subjects With Elevated Liver Fat and High BMI Volunteers

A Phase 2 study of NASH - Nonalcoholic Steatohepatitis, sponsored by Rivus Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
80
Enrollment target
1
Study location

NCT04874233 is a Phase 2 study of NASH - Nonalcoholic Steatohepatitis that has completed, run by Rivus Pharmaceuticals. The registered enrollment target is 80 participants, below the 266-participant average among 27 other NASH - Nonalcoholic Steatohepatitis trials with a reported enrollment target (70% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04874233, a Phase 2 study of NASH - Nonalcoholic Steatohepatitis, has completed, sponsored by Rivus Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

This is a Phase 2a, randomized, parallel-group, placebo-controlled, double-blind, repeated-dose study to evaluate the safety and efficacy of three oral dose levels of HU6 compared to placebo over the course of 61 days in subjects with high BMI and evidence of elevated liver fat.

Interventions

  • DRUG Placebo
  • DRUG HU6

Study Locations (1)

Minnesota

  • Prism Clinical Research - Minneapolis

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2021-04-19
Est. Completion 2021-12-15
Phase Phase 2

Sponsor

Rivus Pharmaceuticals

10 total trials

What the Registry Record Tells You About NCT04874233

The ClinicalTrials.gov registry entry for NCT04874233 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 266-participant average among 27 other NASH - Nonalcoholic Steatohepatitis trials with a reported enrollment target (70% lower). The listed sponsor is Rivus Pharmaceuticals, which has 10 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with NASH - Nonalcoholic Steatohepatitis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT04874233 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT04874233 about?

NCT04874233 is a clinical study titled "Phase 2a Study of HU6 in Subjects With Elevated Liver Fat and High BMI Volunteers". This is a Phase 2a, randomized, parallel-group, placebo-controlled, double-blind, repeated-dose study to evaluate the safety and efficacy of three oral dose levels of HU6 compared to placebo over the course of 61 days in subjects with high BMI and evidence of elevated liver fat.

What is the current status of trial NCT04874233?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2021-04-19. Estimated completion is 2021-12-15.

What conditions does trial NCT04874233 study?

This clinical trial studies the following conditions: NASH - Nonalcoholic Steatohepatitis.

What interventions are being tested in trial NCT04874233?

The interventions under investigation include: Placebo (DRUG), HU6 (DRUG).

Who is sponsoring clinical trial NCT04874233?

This trial is sponsored by Rivus Pharmaceuticals, which has 10 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04874233 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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