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NCT04832009 · ClinicalTrials.gov registry record · Early Phase 1
Reversing Glucose and Lipid-mediated Vascular Dysfunction
A Early Phase 1 study of Hypertension and Blood Pressure, sponsored by University of Kansas Medical Center.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 46
- Enrollment target
- 1
- Study location
NCT04832009: Recruiting Early Phase 1 study of Hypertension and Blood Pressure, sponsored by University of Kansas Medical Center.
NCT04832009 is a Early Phase 1 study of Hypertension and Blood Pressure that is actively recruiting participants, run by University of Kansas Medical Center. The registered enrollment target is 46 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04832009, a Early Phase 1 study of Hypertension and Blood Pressure, is actively recruiting participants, sponsored by University of Kansas Medical Center.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 46 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of our study is to understand the extent to which the blood vessels are affected by glucose and fat (lipids) in lean healthy adults and if these changes in the blood vessels contribute to the development of high blood pressure.
Primary Outcome
The difference in sympathetic-vascular transduction (mmHg) between ascorbic acid and placebo infusion will be taken as a measure of the modulation of SVT by oxidative stress.
Conditions Studied
Interventions
- DRUG Saline
- DRUG Ascorbic acid
- DRUG Dextrose 20 % in 500 ML Injection
- DRUG Intralipid
Study Locations (1)
Kansas
- University of Kansas Medical Center - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2022-05-09 |
| Est. Completion | 2027-08-01 |
| Phase | Early Phase 1 |
What NCT04832009 shows while recruiting
NCT04832009 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Hypertension appearing as the primary indexed condition, and to 4 interventions - of which Saline is the first listed.
NCT04832009 reports a single indexed study location in Kansas.
Frequently Asked Questions
What is clinical trial NCT04832009 about?
NCT04832009 is a clinical study titled "Reversing Glucose and Lipid-mediated Vascular Dysfunction". The purpose of our study is to understand the extent to which the blood vessels are affected by glucose and fat (lipids) in lean healthy adults and if these changes in the blood vessels contribute to the development of high blood pressure.
What is the current status of trial NCT04832009?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 46 participants. The study started on 2022-05-09. Estimated completion is 2027-08-01.
What conditions does trial NCT04832009 study?
This clinical trial studies the following conditions: Hypertension, Blood Pressure.
What interventions are being tested in trial NCT04832009?
The interventions under investigation include: Saline (DRUG), Ascorbic acid (DRUG), Dextrose 20 % in 500 ML Injection (DRUG), Intralipid (DRUG).
Who is sponsoring clinical trial NCT04832009?
This trial is sponsored by University of Kansas Medical Center, which has 408 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04832009 being conducted?
This trial has 1 study location across Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypertension
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04832009's enrollment target sits among peer trials
46 378th of 470 higher than 92 of 470 other Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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