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NCT04546126 · ClinicalTrials.gov registry record · Early Phase 1
Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Groups 2, 3 & 4)
A Early Phase 1 study of Hypertension and Cholesterol, sponsored by Benjamin Viglianti.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 24
- Enrollment target
- 2
- Study locations
NCT04546126: Recruiting Early Phase 1 study of Hypertension and Cholesterol, sponsored by Benjamin Viglianti.
NCT04546126 is a Early Phase 1 study of Hypertension and Cholesterol that is actively recruiting participants, run by Benjamin Viglianti. The registered enrollment target is 24 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04546126, a Early Phase 1 study of Hypertension and Cholesterol, is actively recruiting participants, sponsored by Benjamin Viglianti.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 24 participants
- Enrollment target
- 2
- Study locations
Study Summary
This study will evaluate the feasibility of using a sub-therapeutic dose of a fluorine-18 analogue of NP-59 (\[18F\]FNP-59) to image the adrenal gland. Some participants are healthy normal subjects but have undergone interventions to manipulate hormones while other participants have known adrenal pathology.
Primary Outcome
SUV will be reported. Both maximal and average SUVs will be calculated
Conditions Studied
Interventions
- DRUG Dexamethasone (Group 2)
- DRUG Cosyntropin (Group 3)
- COMBINATION_PRODUCT PET/CT Scan with FNP-59
Study Locations (2)
Michigan
- University of Michigan - Ann Arbor
- BAMF Health, Inc. - Grand Rapids
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2021-11-01 |
| Est. Completion | 2026-12 |
| Phase | Early Phase 1 |
What NCT04546126 shows while recruiting
NCT04546126 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (99% lower).
The record links to 3 conditions, with Hypertension appearing as the primary indexed condition, and to 3 interventions - of which Dexamethasone (Group 2) is the first listed.
NCT04546126 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT04546126 about?
NCT04546126 is a clinical study titled "Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Groups 2, 3 & 4)". This study will evaluate the feasibility of using a sub-therapeutic dose of a fluorine-18 analogue of NP-59 (\[18F\]FNP-59) to image the adrenal gland. Some participants are healthy normal subjects but have undergone interventions to manipulate hormones while other participants have known adrenal pa...
What is the current status of trial NCT04546126?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 24 participants. The study started on 2021-11-01. Estimated completion is 2026-12.
What conditions does trial NCT04546126 study?
This clinical trial studies the following conditions: Hypertension, Cholesterol, Radiotracer.
What interventions are being tested in trial NCT04546126?
The interventions under investigation include: Dexamethasone (Group 2) (DRUG), Cosyntropin (Group 3) (DRUG), PET/CT Scan with FNP-59 (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT04546126?
This trial is sponsored by Benjamin Viglianti, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04546126 being conducted?
This trial has 2 study locations across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypertension
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04546126's enrollment target sits among peer trials
24 429th of 470 higher than 38 of 470 other Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Group 1)
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