Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04831125 · ClinicalTrials.gov registry record
Conduction System Pacing International Registry (CONSPIRE)
A clinical trial of Heart Failure and Bradyarrhythmia, sponsored by University of Chicago.
- Completed
- Registry status
- 383
- Enrollment target
- 8
- Study locations
NCT04831125: Completed study of Heart Failure and Bradyarrhythmia, sponsored by University of Chicago.
NCT04831125 is a study of Heart Failure and Bradyarrhythmia that has completed, run by University of Chicago. The registered enrollment target is 383 participants, below the 2,048-participant average among 397 other Heart Failure trials with a reported enrollment target (81% lower). The trial reports 8 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04831125, a study of Heart Failure and Bradyarrhythmia, has completed, sponsored by University of Chicago.
- COMPLETED
- Registry status
- 383 participants
- Enrollment target
- 8
- Study locations
Study Summary
The purpose of this registry study is to collect information about routine clinical practices with device implantation to treat bradycardia and cardiac systolic dysfunction (heart rhythm disorders) across global centers of excellence in cardiac pacing. In particular, this study will examine the use of conduction system pacing (CSP) in clinical practice. Information collected in the registry will help researchers better characterize strengths and limitations of current technology and treatments.
Primary Outcome
Data will be collected on CSP lead position based on reported anatomical position (e.g., His bundle location, left bundle branch area or left bundle branch pacing location, or left ventricular septal pacing location)
Conditions Studied
Interventions
- OTHER Data collection
Study Locations (8)
Other
- Maastricht University Medical Center - Maastricht
- Health Research Institute Hospital La Fe - Valencia
- Lund University - Lund
Pennsylvania
- University of Pennsylvania - Philadelphia
- Geisinger Wyoming Valley Medical Center - Wilkes-Barre
Arizona
- University of Arizona - Tucson
Illinois
- University of Chicago - Chicago
New York
- Icahn School of Medicine at Mount Sinai & Mount Sinai Hospital - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 383 participants |
| Start Date | 2021-04-04 |
| Est. Completion | 2026-02-05 |
What the finished NCT04831125 record still lists
NCT04831125 is an observational study that tracks outcomes without assigning an intervention. The registered 383 participants enrollment target is mid-sized for trials with a published cap, below the 2,048-participant average among 397 other Heart Failure trials with a reported enrollment target (81% lower).
The record links to 2 conditions, with Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which Data collection is the first listed.
NCT04831125 lists 8 locations in 5 states (Other, Pennsylvania, Arizona).
Frequently Asked Questions
What is clinical trial NCT04831125 about?
NCT04831125 is a clinical study titled "Conduction System Pacing International Registry (CONSPIRE)". The purpose of this registry study is to collect information about routine clinical practices with device implantation to treat bradycardia and cardiac systolic dysfunction (heart rhythm disorders) across global centers of excellence in cardiac pacing. In particular, this study will examine the use ...
What is the current status of trial NCT04831125?
This trial is currently completed. The enrollment target is 383 participants. The study started on 2021-04-04. Estimated completion is 2026-02-05.
What conditions does trial NCT04831125 study?
This clinical trial studies the following conditions: Heart Failure, Bradyarrhythmia.
What interventions are being tested in trial NCT04831125?
The interventions under investigation include: Data collection (OTHER).
Who is sponsoring clinical trial NCT04831125?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04831125 being conducted?
This trial has 8 study locations across Arizona, Illinois, New York, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04831125's enrollment target sits among peer trials
383 118th of 397 higher than 280 of 397 other Heart Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Early Feasibility Study of the NORM™ System in Heart Failure Patients (FUTURE-HFII)
RECRUITING · NA
-
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
RECRUITING · NA
-
iCardia4HF: Multi-component mHealth Intervention for Patients With Heart Failure
RECRUITING · NA
-
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients with Heart Failure Who Are Intolerant or Not Eligible for Treatment with Steroidal Mineralocorticoid Receptor Antagonists
RECRUITING · Phase 3
-
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure
RECRUITING
-
Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence
RECRUITING
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT06056830 · 383 participants · Phase 3
Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy
- NCT06277661 · 384 participants · NA
The Mom and Infant Outcomes (MOMI) Study
- NCT06372964 · 384 participants · Phase 3
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
- NCT06501040 · 384 participants · NA
Increasing Knowledge and Interest in Cancer Clinical Trials
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI