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NCT04750616 · ClinicalTrials.gov registry record · Phase 2
NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial
A Phase 2 study of Acute Kidney Injury and Ischemia Reperfusion Injury, sponsored by Kaiser Permanente.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 304
- Enrollment target
- 1
- Study location
NCT04750616: Recruiting Phase 2 study of Acute Kidney Injury and Ischemia Reperfusion Injury, sponsored by Kaiser Permanente.
NCT04750616 is a Phase 2 study of Acute Kidney Injury and Ischemia Reperfusion Injury that is actively recruiting participants, run by Kaiser Permanente. The registered enrollment target is 304 participants, below the 2,327-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04750616, a Phase 2 study of Acute Kidney Injury and Ischemia Reperfusion Injury, is actively recruiting participants, sponsored by Kaiser Permanente.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 304 participants
- Enrollment target
- 1
- Study location
Study Summary
A Randomized, Double-blind, placebo-controlled Trial to Evaluate the Efficacy of Oral Nam for the Prevention of Acute Kidney Injury in Patients Undergoing On-Pump Cardiac Surgery
Primary Outcome
Troponin T AUC, composed of single daily serum measurements
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Niacinamide
Study Locations (1)
California
- Kaiser Permanente San Francisco Medical Center - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 304 participants |
| Start Date | 2021-09-13 |
| Est. Completion | 2025-06-30 |
| Phase | Phase 2 |
What NCT04750616 shows while recruiting
NCT04750616 is an interventional study that assigns participants to a tested intervention. The registered 304 participants enrollment target is mid-sized for trials with a published cap, below the 2,327-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (87% lower).
The record links to 3 conditions, with Acute Kidney Injury appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04750616 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04750616 about?
NCT04750616 is a clinical study titled "NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial". A Randomized, Double-blind, placebo-controlled Trial to Evaluate the Efficacy of Oral Nam for the Prevention of Acute Kidney Injury in Patients Undergoing On-Pump Cardiac Surgery
What is the current status of trial NCT04750616?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 304 participants. The study started on 2021-09-13. Estimated completion is 2025-06-30.
What conditions does trial NCT04750616 study?
This clinical trial studies the following conditions: Acute Kidney Injury, Ischemia Reperfusion Injury, Myocardial Injury.
What interventions are being tested in trial NCT04750616?
The interventions under investigation include: Placebo (DRUG), Niacinamide (DRUG).
Who is sponsoring clinical trial NCT04750616?
This trial is sponsored by Kaiser Permanente, which has 294 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04750616 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Kidney Injury
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04750616's enrollment target sits among peer trials
304 23rd of 74 higher than 52 of 74 other Acute Kidney Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Kidney Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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