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RECRUITING Phase 2

NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial

NCT04750616 · View on ClinicalTrials.gov ↗

Study Summary

A Randomized, Double-blind, placebo-controlled Trial to Evaluate the Efficacy of Oral Nam for the Prevention of Acute Kidney Injury in Patients Undergoing On-Pump Cardiac Surgery

Interventions

  • DRUG Placebo
  • DRUG Niacinamide

Study Locations (1)

California

  • Kaiser Permanente San Francisco Medical Center — San Francisco

Trial Details

FieldValue
Enrollment Target 304 participants
Start Date 2021-09-13
Est. Completion 2025-06-30
Phase Phase 2

Sponsor

Kaiser Permanente

132 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04750616

The ClinicalTrials.gov registry entry for NCT04750616 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 304 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Kaiser Permanente, which has 132 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Acute Kidney Injury appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04750616 reports 1 study location spanning 1 distinct geographic area — top geographies include California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04750616 about?

NCT04750616 is a clinical study titled "NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial". A Randomized, Double-blind, placebo-controlled Trial to Evaluate the Efficacy of Oral Nam for the Prevention of Acute Kidney Injury in Patients Undergoing On-Pump Cardiac Surgery

What is the current status of trial NCT04750616?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 304 participants. The study started on 2021-09-13. Estimated completion is 2025-06-30.

What conditions does trial NCT04750616 study?

This clinical trial studies the following conditions: Acute Kidney Injury, Ischemia Reperfusion Injury, Myocardial Injury. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04750616?

The interventions under investigation include: Placebo (DRUG), Niacinamide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04750616?

This trial is sponsored by Kaiser Permanente, which has 132 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04750616 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial