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NCT04683640 · ClinicalTrials.gov registry record · Phase 2
Latent Aging Mechanisms in Pain and Sleep
A Phase 2 study of Chronic Pain, sponsored by University of Florida.
- Completed
- Registry status
- Phase 2
- Development phase
- 33
- Enrollment target
- 1
- Study location
NCT04683640: Completed Phase 2 study of Chronic Pain, sponsored by University of Florida.
NCT04683640 is a Phase 2 study of Chronic Pain that has completed, run by University of Florida. The registered enrollment target is 33 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04683640, a Phase 2 study of Chronic Pain, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 33 participants
- Enrollment target
- 1
- Study location
Study Summary
Chronic pain is a serious public health problem in older adults depending on the pain condition, and the capacity to sleep properly changes with age. Given the potential mechanistic role of GABA (gamma-aminobutyric acid) in both conditions, based on our preliminary data, this proposal will determine the effect of oral GABA administration in sleep quality and pain in older adults with chronic pain and sleep disorders as well as to characterize the potential neurobiological mechanisms involved in both illnesses.
Primary Outcome
The Pittsburgh Sleep Quality Index (PSQI) is a self-report questionnaire that assesses sleep quality over the past month. It consists of 19 items grouped into seven components. Each component is scored from 0 to 3, and the component scores are summed to yield a global total score ranging from 0 to 21. Higher scores indicate worse sleep quality. A total score greater than 5 is typically used to distinguish poor sleepers from good sleepers.
Conditions Studied
Interventions
- DRUG Placebo
- DIETARY_SUPPLEMENT GABA
Study Locations (1)
Florida
- University of Florida - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2021-04-02 |
| Est. Completion | 2024-05-30 |
| Phase | Phase 2 |
What the finished NCT04683640 record still lists
NCT04683640 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Chronic Pain appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04683640 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT04683640 about?
NCT04683640 is a clinical study titled "Latent Aging Mechanisms in Pain and Sleep". Chronic pain is a serious public health problem in older adults depending on the pain condition, and the capacity to sleep properly changes with age. Given the potential mechanistic role of GABA (gamma-aminobutyric acid) in both conditions, based on our preliminary data, this proposal will determine...
What is the current status of trial NCT04683640?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 33 participants. The study started on 2021-04-02. Estimated completion is 2024-05-30.
What conditions does trial NCT04683640 study?
This clinical trial studies the following conditions: Chronic Pain.
What interventions are being tested in trial NCT04683640?
The interventions under investigation include: Placebo (DRUG), GABA (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT04683640?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04683640 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04683640's enrollment target sits among peer trials
33 240th of 301 higher than 60 of 301 other Chronic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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